Results 131 to 140 of about 4,058,838 (360)

Profiles of physical, emotional and psychosocial wellbeing in the Lothian birth cohort 1936 [PDF]

, 2012
Background Physical, emotional, and psychosocial wellbeing are important domains of function. The aims of this study were to explore the existence of separable groups among 70-year olds with scores representing physical function, perceived quality of ...
AE Raftery, AJ Garfein, AJ Gow, AJ Gow, AJ Lamond, AL McCuthcheon, AM Freund, Andrea R Zammit, AS Zigmond, BD Cox, C Depp, C Hertzog, CM Callahan, CR Gale, D Gerstorf, D Nagin, D Wechsler, D Wechsler, DE Schoenfeld, DJ Bauer, DK Mroczek, G Andrews, G Celeux, GJ McLachlan, H Okabayashi, HE Nelson, HS Friedman, Ian J Deary, IJ Deary, IJ Deary, IJ Deary, J Smith, J Smith, John M Starr, JW Rowe, KB DeSalvo, KE Markon, KJ Ko, KR Kruger, L Fratiglioni, L Fratiglioni, L Muthén, LF Berkman, M Lövdén, M Rennemark, MM Baltes, P Townsend, PB Baltes, PB Baltes, PT Costa, S Shiovitz-Ezra, Scottish Council for Research in Education, Scottish Council for Research in Education, ST Charles, V Menec, W Johnson, W Johnson, Wendy Johnson, WHOQOL Group, WJ Strawbridge   +59 more
core   +2 more sources

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

RESEARCH ON THERMAL AGING OF INDUSTRIAL ROBOT CABLE SHEATH

Jixie qiangdu, 2021
In the long-term work of industrial robot cables,the mechanical properties will be insufficient due to aging,which will affect the normal operation of the robot.
ZHOU ChunLin, WU Can, YANG Kai, NI Jing
doaj  

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Lightning Pin Injection Test: MOSFETS in "ON" State [PDF]

The test objective was to evaluate MOSFETs for induced fault modes caused by pin-injecting a standard lightning waveform into them while operating. Lightning Pin-Injection testing was performed at NASA LaRC.
Celaya, Jose R., Ely, Jay J., Koppen, Sandra V., Mielnik, John J., Nguyen, Truong X., Saha, Sankalita, Szatkowski, George N., Vaughan, Roger K., Wysocki, Philip F.   +8 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Designing integrated educational program and investigating its effectiveness on perception of aging in the elderly of Iran

مجله علوم روانشناختی, 2019
Background: Aging can cause negative perceptions for people with the sense of inefficacy. Researches showed the positive effect of good perception to elderly on life quality.
Manijeh Shahbazkhan, Sara Pashang, Biok Tajeri, Alireza Kakavand   +3 more
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Relationship of mechanical characteristics and microstructural features to the time-dependent edge notch sensitivity of inconel 718 sheet [PDF]

Time-dependent notch sensitivity of Inconel 718 sheet was observed at 900 F to 1200 F (482 - 649 C). It occurred when edge-notched specimens were loaded below the yield strength and smooth specimen tests showed that small amounts of creep consumed large ...
Wilson, D. J.
core   +1 more source