Results 131 to 140 of about 1,079,597 (317)
THE PROTHROMBIN TEST AND PIVKA-II IN BREASTFEDINFANTS AGED THE FIRST 6 MONTHS OF LIFE
Neonatology, surgery and perinatal medicine, 2017 Метою нашого дослідження було вивчення вітамін-К-залежних показників протромбінового комплексу гемостазу і змісту субстанції PIVKA-II, як маркера дефіциту вітаміну К, у дітей, які отримують грудне вигодовування від народження до 6 місяців життя.Матеріали та методи.
Ivanko, O. G., Solianik, O. V.
openaire +3 more sources
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, Volume 20, Issue 6, Page 1643-1660, June 2026.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Althea Medical JournalBackground: Aging is associated with declining physical health and decreased quality of life in the elderly population. In response to the rising challenges faced by the aging demographic, this study aimed to investigate the effects of low-impact aerobic
Cahyo Setiawan +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Psihologijske teme, 2018 Cilj je ovoga istraživanja bio ispitati povezanost otvorenosti prema iskustvu i uspješnog starenja, te provjeriti moguću posredujuću ulogu životnih žaljenja zbog propuštenih prilika i pogrešnih akcija u tom odnosu. Povećanje udjela starijih osoba u populaciji potaknulo je usmjeravanje istraživačkog interesa na čimbenike koji doprinose dugovječnosti i ...
Ambrosi-Randić, Neala +2 more
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Stressors and Subjective Cognition in Daily Life: Tests of Physical Activity and Age as Moderators
Psychosomatic MedicineABSTRACT Objective Growing research indicates that daily stress is associated with poorer same-day cognitive performance, for example, memory and attention. However, it is unclear whether this relationship holds across diverse ages and engagement in physical activity (PA), or whether these factors might buffer the ...
Nicole S. Stuart +5 more
openaire +3 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source