Results 151 to 160 of about 5,892,346 (305)

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Physical activity across the life course and neural biomarkers. [PDF]

J Alzheimers Dis
Torres ER, Lopez ED, McBurrows L, Kollmorgen G, Carboni M, Johnson SC, Zetterberg H, Blennow K, Bendlin BB.   +8 more
europepmc   +1 more source

Considering Life Course Concepts [PDF]

The Journals of Gerontology Series B: Psychological Sciences and Social Sciences, 2012
openaire   +3 more sources

Positive Aging: Reconstructing The Life Course [PDF]

, 2006
Gergen, Kenneth J., Gergen, M. M.
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Composite Mesenchymal Stromal Cell Islets: Implications for Transplantation via the Clinically Preferred Intraportal Route

Transplantation Direct, 2018
Chloe L. Rackham, PhD, Paramjeet K. Dhadda, PhD, Sian J.S. Simpson, BSc, Mahdieh Godazgar, BSc, Aileen J.F. King, PhD, Peter M. Jones, PhD   +5 more
doaj   +1 more source

When family caregiving happens: life-course timing and health outcomes in later life. [PDF]

J Gerontol B Psychol Sci Soc Sci
Lee C, Glei DA, Park S, Brown CK, Weinstein M.   +4 more
europepmc   +1 more source

Advanced Life Support Courses [PDF]

Annals of Emergency Medicine, 2016
openaire   +2 more sources