Results 171 to 180 of about 1,443,194 (218)

Life-course socioeconomic status and obesity: scoping review. [PDF]

Popul Health Metr
Adamou H, Paquette MC, François D, Robitaille É, Ouindpanga SS, Lebel A.   +5 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

An umbrella review of psychological capacity and mental health trajectories across the life course. [PDF]

Nat Ment Health
Moreno-Agostino D, Khan N, De Rubeis V, Jacob CM, Banati P, Sadana R, Prina M.   +6 more
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Contribution of Life-Course Socioeconomic Position to Later-Life Brain Volumes in US Hispanic/Latino Adults. [PDF]

Neurology
Filigrana P, Moon JY, Gallo LC, González HM, Lipton RB, Tarraf W, Kaplan RC, Daviglus ML, Testai FD, Marquine MJ, Cai J, Perreira KM, Stickel AM, DeCarli C, Isasi CR.   +14 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Women's health and well-being over the life course: conceptual framing supported by a scoping review. [PDF]

BMJ Open
Iyer A, Sen G, Rao Seshadri S, Snow R, Ataullahjan A, Liang M, Baird S, Drake JK, Sharafi L, Bhutta Z.   +9 more
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Adverse Childhood Experiences and Life Course Adversity Related to Geriatric Syndromes: A Narrative Review. [PDF]

Medicina (Kaunas)
Reyes-Ortiz CA, Castro-Florez X, Ocampo-Chaparro JM.   +2 more
europepmc   +1 more source

Life-course socio-economic factors associated with frailty in later life. [PDF]

J Frailty Aging
Christensen MG, Jacobsen KK, Nilsson CJ, Jepsen R, Thygesen LC, Suetta C, Holm EA.   +6 more
europepmc   +1 more source