Results 211 to 220 of about 5,863,535 (304)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Life-Course Burden of Blood Pressure Is Associated With Midlife Cognitive Function. [PDF]

Hypertension
Chen W, Li C, Zhang R, Huang Z, Li S, De Anda-Duran I, Carmichael OT, Ma H, Wang X, Kelly TN, He J, Bazzano LA.   +11 more
europepmc   +1 more source

LOCATIONAL BEHAVIOUR OF YOUNG FIRMS: A LIFE COURSE PERSPECTIVE [PDF]

Schutjens, Veronique, Stam, Erik
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Position Statement on Cardiometabolic Health Across the Woman's Life Course - 2025. [PDF]

Rev Bras Ginecol Obstet
de Oliveira GMM, de Almeida MCC, Valério CM, Giuffrida F, Espíndola LN, Izar MCO, Marques-Santos C, Freire CMV, Albuquerque CJDM, Chagas ACP, Précoma DB, Mesquita ET, Saraiva JFK, Costa MENC, Lemke VMG, de Lucena AJG, Brandão AA, Fagundes AAP, Macedo AVS, Polanczyk CA, Leitão CB, Silveira DS, Coutinho EDR, Nahas EAP, Alexandre ERG, Campana EMG, Bragança EOV, Colombo FMC, Barbosa ICQ, Rivera IR, Kulak J, Salles JEN, de Sá JR, Soares JM, Dourado LA, Moura LZ, Magalhães LBNC, Pompei LM, Passaglia LG, Assad MHV, Rodrigues MAH, Rivera MAM, Lopes MAAAM, Paiva MSMO, de Castro ML, Campos MDSB, de Souza OF, de Medeiros OO, Freitas RAP, de Carvalho RCM, da Silva SCTF, Rodrigues TCV, Avila WS, da Silva WS, Nazima WI, da Costa-Paiva LHS, Wender MCO.   +56 more
europepmc   +1 more source

Subjective well-being over the life course: Conceptualizations and evaluations [PDF]

, 2010
Plagnol, A.
core  

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source