Results 51 to 60 of about 9,912,419 (304)

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source

Mode of infant feeding, eating behaviour and anthropometry in infants at 6-months of age born to obese women – a secondary analysis of the UPBEAT trial

BMC Pregnancy and Childbirth, 2018
Background Maternal obesity and rapid infant weight gain have been associated with increased risk of obesity in childhood. Breastfeeding is suggested to be protective against childhood obesity, but no previous study has addressed the potential benefit of
Nashita Patel, Kathryn V. Dalrymple, Annette L. Briley, Dharmintra Pasupathy, Paul T. Seed, Angela C. Flynn, Lucilla Poston, on behalf of the UPBEAT Consortium   +7 more
doaj   +1 more source

Systematic review and narrative synthesis of suicide prevention in high-schools and universities: a research agenda for evidence-based practice

BMC Public Health, 2021
Background Youth suicide prevention in high-schools and universities is a public health priority. Our aim was to propose a research agenda to advance evidence-based suicide prevention in high-schools and universities by synthesizing and critically ...
Elsie Breet, Matsie Matooane, Mark Tomlinson, Jason Bantjes   +3 more
doaj   +1 more source

Biphasic Clinical Course of Pediatric Cytomegalovirus‐Associated Immune Thrombocytopenia: Early Poor Treatment Response but Favorable Long‐Term Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad, Ohad Atia, Osama Tanous, Dafna Brik Simon, Michal Dvori, Miriam Cohen, Tracie A. Goldberg, Efraim Bilavsky, Joanne Yacobovich, Orna Steinberg‐Shemer   +9 more
wiley   +1 more source

Patient-oriented unsupervised learning to uncover the patterns of multimorbidity associated with stroke using primary care electronic health records

BMC Primary Care
Background We aimed to identify and characterise the longitudinal patterns of multimorbidity associated with stroke. Methods We used an unsupervised patient-oriented clustering approach to analyse primary care electronic health records (EHR) of 30 common
Marc Delord, Xiaohui Sun, Annastazia Learoyd, Vasa Curcin, Charles Wolfe, Mark Ashworth, Abdel Douiri   +6 more
doaj   +1 more source

An overview of health workforce education and accreditation in Africa: implications for scaling-up capacity and quality

Human Resources for Health, 2022
Background For countries to achieve universal health coverage, they need to have well-functioning and resilient health systems. Achieving this requires a sufficient number of qualified health workers and this necessitates the importance of investments in
Sunny C. Okoroafor, Adam Ahmat, James Avoka Asamani, Jean Jacques Salvador Millogo, Jennifer Nyoni   +4 more
doaj   +1 more source

Parents of Youth With Cancer Report on Their Psychosocial Care: iSTEPPP Survey Finds Alignment and Gaps With Standards

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Standards for Psychosocial Care for Children with Cancer and Their Families guide the provision of comprehensive psychosocial care. Parallel to research characterizing implementation of the Standards from the perspective of providers, this study examines implementation of the Standards from the perspective of parents of youth ...
Emily M. Pariseau, Kimberly Buff, Michele A. Scialla, Kimberly S. Canter, Lori Wiener, Victoria Sardi‐Brown, Julia B. Tager, Kamyar Arasteh, Anne E. Kazak   +8 more
wiley   +1 more source

Developmental and Life-Course Criminology

, 2019
This chapter provides a brief overview of developmental and life-course criminology. These approaches are concerned with the study of the development of offending over the course of one's life, from onset to persistence and, eventually, desistance ...
Kazemian, Lila, Piquero, Alex R, Farrington, David P   +2 more
core   +1 more source

A life course approach to cardiovascular aging. [PDF]

, 2015
A life course approach in epidemiology investigates the biological, behavioral and social pathways that link physical and social exposures and experiences during gestation, childhood, adolescence and adult life, and across generations, to later-life ...
Hardy, R, Lawlor, DA, Kuh, D., Hardy, R., Kuh, D, Lawlor, D.A.   +5 more
core   +1 more source