Results 191 to 200 of about 1,623,376 (313)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Life cycle assessment of a wood-aluminium window according to European norms. [PDF]

Sci Rep
Sečkár M, Schwarz M, Majer D.
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Mechanistic and Life-Cycle Framework for Green Nanomaterials in Atmospheric Water Harvesting. [PDF]

Nanomaterials (Basel)
Al-Sadeq N, Abdullah JAA, Romero A, Perez-Puyana VM.   +3 more
europepmc   +1 more source

The Protozoon Life-Cycle [PDF]

Science, 1906
openaire   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

ILCIDAF Italian Life Cycle Inventory Database of Agrifoods (PRIN2017: 2017EC9WF2)

L’assenza di una banca dati italiana per gli studi di Life Cycle Assessment (LCA) dei prodotti agroalimentari è un tema molto sentito dagli esperti e dagli studiosi del settore, poichè le banche dati attualmente disponibili in commercio sono di ...
Bruno Notarnicola, Teresa Gullotta, Giacomo Falcone, Ioannis Arzoumanidis, Luigia Petti, Alexander Renzulli, Roberta Salomone, Rosa Di Capua, Maurizio Del Molfetta, Andrea Raggi, Giuseppe Saija, Francesco Astuto, Giovanni Mondello, Manuela D'Eusanio, Patrizia Primerano, Alfio Strano, Antonio Fazari   +16 more
core  

AuLCA: augmented life cycle assessment for chemical data gaps.

Green Chem
Hoepfner MG, Jakobs D, Santos LF, Guillén-Gosálbez G.   +3 more
europepmc   +1 more source

Life Cycle Assessment of Microplastic Fouling Mitigation Strategies in Membrane Filtration. [PDF]

Membranes (Basel)
Hafyan RH, Indrakumar V, Lee J, Gadkari S.   +3 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source