Results 81 to 90 of about 1,426,333 (294)

Land use planning strategies for food versus non-food estate sustainable farming [PDF]

Global Journal of Environmental Science and Management
BACKGROUND AND OBJECTIVES: Food estate initiative is an Indonesian government program designed to achieve food security though the cultivation of strategic commodities on large-scale agricultural land. Despite being controversial due to the scale of land
D. Juhandi, D.H. Darwanto, M. Masyhuri, J.H. Mulyo, N.A. Sasongko, H.L. Susilawati, A. Meilin, T. Martini   +7 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Root growth and arbuscular mycorrhizal fungi on woody plants for vegetative stabilization of tropical slopes [PDF]

Global Journal of Environmental Science and Management
BACKGROUND AND OBJECTIVES: Plant growth is improved by arbuscular mycorrhizal fungi, although they have not been researched for slope stability. These fungal inoculations and bamboo interventions may promote root development toward the slip plane ...
I.G. Tejakusuma, E.H. Sittadewi, T. Handayani, T. Hernaningsih, W. Wisyanto, A. Rifai   +5 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Exploring the potential of water hyacinth weed (Pontederia crassipes) as an environmentally friendly antifungal to realize sustainable development in lakes: A review

Case Studies in Chemical and Environmental Engineering
Pontederia crassipes is an invasive plant in all aquatic environment, especially in stagnant water such as lakes. This plant contains bioactive compounds with environmentally friendly antifungal properties.
Rita Dwi Ratnani, Forita Dyah Arianti, Nugroho Adi Sasongko   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Evaluating the impacts of environmental and human health of the critical minerals mining and processing industries in Indonesia using life cycle assessment

Case Studies in Chemical and Environmental Engineering
The critical minerals industries in Indonesia may pose possible environmental and human health risks due to the release of pollutants into soil, water, and air, as well as the use of materials and energy.
Yoyon Wahyono, Nugroho Adi Sasongko, Allan Trench, Martin Anda, Hadiyanto Hadiyanto, Nyayu Aisyah, Anisah Anisah, Novy Ariyanto, Isnaeni Kumalasari, Virny Zasyana Eka Putri, Mutia Citrawati Lestari, Lambas Parlaungan Panggabean, Rohmadi Ridlo, Sundari Sundari, Anissa Dewi Suryaningtyas, Endah Dwi Novianti, Muhammad Raihan Farras Hakim, Anggara Lomak Prihatin, Hashfi Hawali Abdul Matin   +18 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source