Results 61 to 70 of about 1,910,644 (290)

Streamlined life cycle assessment of transparent silica aerogel made by supercritical drying [PDF]

, 2012
This is the post-print version of the Article. The official published version can be accessed from the link below - Copyright @ 2011 ElsevierWhen developing sustainable building fabric technologies, it is essential that the energy use and CO2 burden ...
Birks, T, Craig, S, Dowson, M, Grogan, M, Harrison, DJ   +4 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Renewable energy potential of rice straw and paunch manure as bioethanol feedstocks in Central Java, Indonesia

Case Studies in Chemical and Environmental Engineering
Almost all farmers are unaware that rice straw and paunch manure are potential feedstocks for bioethanol besides organic fertilizer, biochar, and biogas.
Forita Dyah Arianti, Joko Triastono, Miranti Dian Pertiwi, Agung Prabowo, Teguh Prasetyo, Chanifah, Bambang Haryanto, Megawati, Widi Astuti, Ira Nurhayati Djarot, Arif Dwi Santoso, Sri Peni Wijayanti   +11 more
doaj   +1 more source

Life Cycle Assessment, Life cycle thinking– Hungarian case study [PDF]

, 2009
LCA and life cycle thinking are used in a variety of applications to help decision. Both of them enable identification and quantification of environmental impacts of a product, process or human activity.
Szita, K. Toth
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Buffalo rumen microbial cellulase as a candidate enzyme for hydrolysis of rice straw into glucose: A preliminary study

Open Veterinary Journal
Background: The buffalo rumen microbiome is enriched in functional genes, notably those encoding betaglucosidase which participate in polysaccharide breakdown.
Agung Prabowo, Slamet Hartanto, Dini Dwi Ludfiani, Bambang Haryanto, Miranti Dian Pertiwi, Abd. Azis Wasil, Maya Larasati Donna Wardani, Nandari Dyah Suretno, Rini Nur Hayati, Forita Dyah Arianti, Arif Dwi Santoso, Megawati Megawati, Widi Astuti, Nuruliarizki Shinta Pandupuspitasari, Asih Kurniawati, Zaenal Bachruddin   +15 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source