Results 71 to 80 of about 462,001 (256)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Barriers to the Adoption of Biogas Technology in Smallholder Dairy Farming in Indonesia: A Case Study in Semarang Regency, Central Java [PDF]

BIO Web of Conferences
This study aims to identify and analyze the barriers faced by dairy farmers in adopting biogas technology in Manggihan Village, Semarang Regency. This village was selected as a case study due to its significant trend of increasing biogas installations ...
Haryanto Bambang, Sutaryo Sutaryo, Purnomoadi Agung, Purbowati Endang, Putra Farhan Akmala, Chanifah Chanifah   +5 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Comparative Study of NIR-Based Machine Learning for Predicting Soil Nutrients in Indonesian Farmlands

Acta Technologica Agriculturae
This study evaluates the efficacy of machine learning models for predicting soil nitrogen (N), phosphorus (P), and potassium (K) concentrations from near-infrared (NIR) spectral data (750–2499 nm).
Adnan Adnan, Ramdhani Taufik Iqbal, Suryana Yaya, Aziz Abdul, Rochmadi Taslim, Kamaruddin Amrullah, Faiza Ninon Nurul   +6 more
doaj   +1 more source

The Impact of Input Tariffs on Gender Inequality: An Empirical Study in Indonesia

Journal of Indonesian Economy and Business
Introduction/Main Objectives: Discrimination between male and female workers occurs because of the difference in the “endowment” and social and cultural norms, especially in developing countries. This study aims to examine the impact of input tariffs on
Noorish Heldini
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Synergistic Effects of Lignocellulosic Baglog Compost and Biochar on Tomato Plant Growth

BioResources
Indonesian agriculture faces multifaceted challenges, particularly the need to enhance productivity while maintaining environmental sustainability to ensure high-quality food production.
Titin Handayani, Septi Syahrani, Ira Nurhayati Djarot, Agusta Samodra Putra, Netty Widyastuti, Akhmad Rifai, Amita Indah Sitomurni, Diana Nurani, Djatmiko Pinardi, Noorwitri Utami, Nuha Nuha, Sri Peni Wijayanti, Ari Kabul Paminto, Anisa Lutfia, Afifah Nurmala Karima, Hanifah Nisrina, Azalea Eugenie, Rizki Amaliyah, Arief Barkah   +18 more
doaj  

Estimating a national critical mineral security index in Indonesia using analytical hierarchy process

Environmental and Sustainability Indicators
Critical minerals are key to guaranteeing energy security and economic stability in a nation. Indonesia, as the largest country in Southeast Asia, has significant reserves of critical minerals.
Nyayu Aisyah, Nugroho Adi Sasongko, Yoyon Wahyono, Martin Anda, Allan Trench   +4 more
doaj   +1 more source