Results 61 to 70 of about 895,491 (343)

Life cycle environmental impact and economic assessment of British Wool face masks

open access: yesCleaner Environmental Systems, 2022
The purpose of this paper is the comparison of the environmental performance between a reusable face mask, made from British Wool, a single-use conventional mask, made of polypropylene (PP), and a reusable cotton mask, using Life Cycle Assessment.
Athanasios Angelis-Dimakis   +5 more
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Development of a Novel Hybrid Thermoplastic Material and Holistic Assessment of Its Application Potential

open access: yesAerospace, 2021
Τhe development of a novel hybrid thermoplastic prepreg material enabling the fabrication of next-generation recyclable composite aerostructures produced by affordable, automated technologies is presented in the present work.
Christos V. Katsiropoulos   +3 more
doaj   +1 more source

Sustainability in the product design: A review of recent development based on LCA [PDF]

open access: yes, 2018
In order to achieve sustainable product design process, aspects such of environmental, economic and social should be balanced. This paper discussed on sustainability of product design, conceptual basis of life cycle assessment (LCA), review of LCA at ...
Hassan, Mohd Fahrul   +3 more
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

A Framework for Life Cycle Sustainability Assessment of Road Salt Used in Winter Maintenance Operations [PDF]

open access: yes, 2016
It is important to assess from a holistic perspective the sustainability of road salt widely used in winter road maintenance (WRM) operations. The importance becomes increasingly apparent in light of competing priorities faced by roadway agencies, the ...
Cui, Na, Shi, Xianming, Xie, Ning
core  

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Development of a whole life cycle cost model for electrification options on the UK rail system [PDF]

open access: yes, 2016
Projects to deliver Overhead Line Equipment (OLE) electrification on the UK rail infrastructure system presents technical challenges which the rail industry in Britain have not traditionally had to consider.
Baguley, Paul   +2 more
core   +1 more source

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