Results 141 to 150 of about 908,324 (360)

Modeling spatial variability in the life-cycle costs of low-volume forest roads [PDF]

open access: yes, 2018
Cost estimation is probably the most decisive factor in the process of computer-aided, preliminary planning for low-volume road networks. However, the cost of construction is normally assumed to be route-independent for a specific project area, resulting
Burlet, Edouard   +2 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Life Cycle Assessment-Based Carbon Footprint Accounting Model and Analysis for Integrated Energy Stations in China [PDF]

open access: gold, 2022
Xiaorong Sun   +6 more
openalex   +1 more source

Does It Pay, at the Margin, to Work and Save? -- Measuring Effective Marginal Taxes on Americans' Labor Supply and Saving [PDF]

open access: yes
Building on Gokhale, Kotlikoff, and Sluchynsky's (2002) study of Americans' incentives to work full or part time, this paper uses ESPlanner, a life-cycle financial planning program, in conjunction with detailed modeling of transfer programs to determine ...
David Rapson, Laurence J. Kotlikoff
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

C-STEER: A Dynamic Sentiment-Aware Framework for Fake News Detection with Lifecycle Emotional Evolution

open access: yesInformatics
The dynamic evolution of collective emotions across the news dissemination life-cycle is a powerful yet underexplored signal in affective computing.
Ziyi Zhen, Ying Li
doaj   +1 more source

Evaluation of the HARDMAN comparability methodology for manpower, personnel and training [PDF]

open access: yes
The methodology evaluation and recommendation are part of an effort to improve Hardware versus Manpower (HARDMAN) methodology for projecting manpower, personnel, and training (MPT) to support new acquisition. Several different validity tests are employed
Butler, R.   +3 more
core   +1 more source

The effect of marketing spending on sales in the premium car segment: New evidence from Germany [PDF]

open access: yes, 2012
This paper assesses empirically the relationship between marketing expenditures and sales in the premium car segment in Germany. We employ a new data-set which contains model-specific data on sales (i.e. registrations), restyling activities and marketing
Crespo-Cuaresma, Jesus   +1 more
core  

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