Results 51 to 60 of about 908,324 (360)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
BuildingsThe performance of structures degrades during their service life due to deterioration and extreme events, compromising the social development and economic growth of structure and infrastructure systems.
Ghazanfar Ali Anwar +7 more
doaj +1 more source
Energies, 2020 In this paper, a comprehensive life-cycle assessment (LCA) is carried out in order to evaluate the multiple environmental-health impacts of the biological wastewater treatment of the fish-processing industry throughout its life cycle.
Shinji Takeshita +2 more
doaj +1 more source
Managing Process Variants in the Process Life Cycle [PDF]
, 2007 When designing process-aware information systems, often variants of the same process have to be specified. Each variant then constitutes an adjustment of a particular process to specific requirements building the process context. Current Business Process
Bauer, Th. +2 more
core +3 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Integrated lifecycle management of engineering products
Технічна інженерія, 2023 This article explores modeling and emulation as pivotal approaches to assist the life cycle stages of a machine-building plant, from design and implementation to operation and existing system optimization.
S.V. , O.S. , D.M.
doaj +1 more source
Застосування системного моделювання як засобу комплексної оптимізації життєвого циклу металоріжучого інструменту [PDF]
, 2010 У статті викладено аналіз можливості моделювання життєвого циклу металоріжучого інструменту як системи моделей, кожна з яких відповідає певному етапу життєвого циклу інструменту. Доведено, що моделювання процесу виконання наступних етапів життєвого циклу
Ковальчук, С. С. +1 more
core
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Molecules, 2023 Atmospheric heavy metal pollution presents a severe threat to public health and environmental stability. Transition metal catalysts have emerged as a potent solution for the selective capture and removal of these pollutants.
Qiang Ma +8 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source