Results 51 to 60 of about 10,765,901 (291)

Safety and Effectiveness of a High‐Dose, Tailored Tissue Plasminogen Activator Therapy Protocol: A Joint Pediatric Hematology and Cardiac ICU Quality Improvement Initiative Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric thromboembolism is increasingly encountered in critical care. Systemic thrombolysis with tissue plasminogen activator (tPA) facilitates vessel or valve patency, yet pediatric‐specific protocols remain undefined, and safety concerns persist. Objective To evaluate the efficacy and safety of a tailored, prolonged systemic tPA
Eran Shostak, Oded Gilad, Yael Feinstein, Sigal Nakav, Ofer Schiller, Joanne Yacobovich   +5 more
wiley   +1 more source

Towards Determining Biosignature Retention in Icy World Plumes

Life, 2020
With the discovery of the persistent jets of water being ejected to space from Enceladus, an understanding of the effect of the space environment on potential organisms and biosignatures in them is necessary for planning life detection missions.
Kathryn Bywaters, Carol R. Stoker, Nelio Batista Do Nascimento, Lawrence Lemke   +3 more
doaj   +1 more source

Global Efforts to Reduce Paediatric Cancer Care Disparities in Radiotherapy: A Decade Change

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background We present an update on the status, needs and challenges faced by paediatric imaging and radiotherapy (RT) programmes globally after a previous survey conducted by the International Atomic Energy Agency (IAEA) 10 years prior. Methods We developed and distributed a 121‐question survey to radiation oncologists, medical physicists and ...
Raymond B. Mailhot Vega, Daniel J. Indelicato, Jeanette Parkes, Natia Esiashvili, Josué Hernández Benítez, Miriam Mikhail‐Lette, Olivera Cirajc Bjelac, Daniel Berger, Eva Ciurana, Yavuz Anacak, Lisbeth Cordero‐Mendez   +10 more
wiley   +1 more source

Mechanism study of hollow-structured MOFs improving catalytic performance

Nature Communications
Hollow-structured metal-organic frameworks (MOFs) often exhibit higher catalytic activity than their solid counterparts, but the mechanism behind this enhancement remains controversial due to the lack of direct experimental evidence.
Lindong Ma, Cancan Li, Qingfeng Wei, Zhenjie Xue, Haochen Ye, Xinyuan Zhou, Jikun Yin, Linbo Cao, Meihui Liu, Xiaomeng Yin, Shan Zhu, Zhe Tang, Tie Wang   +12 more
doaj   +1 more source

Mid-infrared supercontinuum-based Fourier transform spectroscopy for plasma analysis

Scientific Reports, 2022
Broadband mid-infrared (MIR) spectroscopy is a well-established and valuable diagnostic technique for reactive plasmas. Plasmas are complex systems and consist of numerous (reactive) types of molecules; it is challenging to measure and control reaction ...
R. Krebbers, N. Liu, K. E. Jahromi, M. Nematollahi, O. Bang, G. Woyessa, C. R. Petersen, G. van Rooij, F. J. M. Harren, A. Khodabakhsh, S. M. Cristescu   +10 more
doaj   +1 more source

Snow Surface Microbial Diversity at the Detection Limit within the Vicinity of the Concordia Station, Antarctica

Life, 2022
The Concordia Research Station provides a unique location for preparatory activities for future human journey to Mars, to explore microbial diversity at subzero temperatures, and monitor the dissemination of human-associated microorganisms within the ...
Alessandro Napoli, Claudia Coleine, Nikea J. Ulrich, Ralf Moeller, Daniela Billi, Laura Selbmann   +5 more
doaj   +1 more source

Lipopolysaccharide Detection across the Kingdoms of Life [PDF]

Trends in Immunology, 2017
Studies in recent years have uncovered a diverse set of eukaryotic receptors that recognize lipopolysaccharide (LPS), the major outer-membrane component of Gram-negative bacteria. Indeed, Toll-like receptors, G-protein-coupled receptors, integrins, receptor-like kinases, and caspases have emerged as important LPS-interacting proteins.
openaire   +2 more sources

Neuropsychological and Educational Outcomes in Shwachman–Diamond Syndrome—A Report From the North American Shwachman–Diamond Syndrome Registry

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Shwachman–Diamond syndrome (SDS) is a rare autosomal recessive ribosomopathy characterized by bone marrow failure and multisystem involvement, with emerging evidence of associated neurocognitive impairment. Methods We conducted a retrospective study of 240 individuals with biallelic Shwachman–Bodian–Diamond syndrome (SBDS) mutations
Jane Koo, Melissa Gerstle, Leah Cheng, Richard Cooper, Katherine Coyne, Claire Dusa, Naomi E. Joffe, Diana Schwarz, Sarah Steltz, Akiko Shimamura, Kasiani C. Myers, Thea Quinton   +11 more
wiley   +1 more source

Identification of ASF1A and HJURP by global H3–H4 histone chaperone analysis as a prognostic two-gene model in hepatocellular carcinoma

Scientific Reports
Hepatocellular carcinoma (HCC) is a malignancy with poor prognosis. Abnormal expression of H3–H4 histone chaperones has been identified in many cancers and holds promise as a biomarker for diagnosis and prognosis.
Yongkang Liu, Shihui Liu, Rui Jing, Congcong Li, Yongqi Guo, Zhiye Cai, Pei Xi, Penggao Dai, Lintao Jia, Hongli Zhu, Xiang Zhang   +10 more
doaj   +1 more source

A Situational Assessment of the Diagnostic Landscape and Organizational Readiness to Implement Next‐Generation Sequencing at Two Childhood Cancer Treatment Centers in Ghana

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Next‐generation sequencing (NGS) has emerged as a promising approach to improve diagnostic accuracy, but its feasibility in low‐ and middle‐income countries remains unknown. This study characterized the diagnostic landscape and assessed organizational readiness for NGS implementation at two childhood cancer treatment centers in Accra ...
Melissa Carvalho, Emmanuella Amoako, Nihad Salifu, Lily Gloria Tagoe, Yaw Bediako, Michelle Hermiston, Catherine Segbefia   +6 more
wiley   +1 more source