Results 141 to 150 of about 7,129,302 (338)
Does Physical Activity Increase Life Expectancy? A Review of the Literature
Journal of Aging Research, 2012 Physical activity reduces many major mortality risk factors including arterial hypertension, diabetes mellitus type 2, dyslipidemia, coronary heart disease, stroke, and cancer.
C. D. Reimers, G. Knapp, A. K. Reimers
doaj +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Does Life Expectancy Affect Per Capita Income Growth? [PDF]
The paper models the behavior of an economy that accumulates capital stock and increases the life expectancy of their inhabitants at the same time. It is shown that as a country develops, it presents initially smaller growth rates on consumption and ...
Rodrigo Cerda
core
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Inequalities in US Life Expectancy by Area Unemployment Level, 1990–2010
Scientifica, 2016 This study examined the association between unemployment and life expectancy in the United States during 1990–2010. Census-based unemployment rates were linked to US county-level mortality data.
Gopal K. Singh, Mohammad Siahpush
doaj +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Life Expectancy at Current Rates vs. Current Conditions
Demographic Research, 2002 Life expectancy is overestimated if mortality is declining and underestimated if mortality is increasing. This is the fundamental claim made by Bongaarts and Feeney (2002) in their article "How Long Do We Live?", where they base their claim on arguments ...
doaj
Life Expectancy and the Environment [PDF]
We present an OLG model in which life expectancy and environmental quality dynamics are jointly determined. Agents may invest in environmental care, depending on how much they expect to live. In turn, environmental conditions affect life expectancy. As a
Mariani, Fabio +2 more
core
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Pensions, Education and Life Expectancy [PDF]
In a two-period model with agent heterogeneity we analyze a pension reform toward a stronger link between contributions and benefits (as recently observed in several countries) in a pension system with a Bismarckian and a Beveridgian component.
Michael Gorski +2 more
core