Results 81 to 90 of about 7,129,302 (338)
Life Expectancy of Mentally Retarded
Pediatric Neurology Briefs, 1990 The life expectancy of profoundly handicapped people with mental retardation is reported from the Lanterman Developmental Center, Pomona, CA.
J Gordon Millichap
doaj +1 more source
Stagnation of life expectancy in Korea in 2018: A cause-specific decomposition analysis.
PLoS ONE, 2020 According to the most recent annual report released by Korea Statistics, the life expectancy at birth (for both sexes) in 2018 was 82.7 years, an increase of 0.0 years over 2017, reflecting the first stagnation in life expectancy since 1960.
Taejae Kim +3 more
doaj +1 more source
BMJ Open, 2022 Objectives To evaluate variability in life expectancy at birth in small areas, describe the spatial pattern of life expectancy, and examine associations between small-area socioeconomic characteristics and life expectancy in a mid-sized city of a middle ...
Ana V Diez Roux +8 more
doaj +1 more source
The Growing Gap in Life Expectancy by Income: Recent Evidence and Implications for the Social Security Retirement Age [PDF]
, 2017 [Excerpt] This report provides a brief overview of the concept of life expectancy, how it is measured, and how it has changed over time in the United States.
Choudhury, Sharmila, Isaacs, Katelin P
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
A Panel Data Study of the Determinants of Life Expectancy in Low Income Countries [PDF]
, 2019 This study attempts to determine the impact of several socioeconomic determinants of life expectancy for 34 low income countries using ordinary least squares linear regression.
Rizzo, Taylor
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source