Results 51 to 60 of about 679,610 (316)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Service life prediction of building materials and components

open access: yes, 2009
This chapter looks at critical problems encountered in the life prediction of building materials and components, and addresses how a database of life estimates can be compiled for the vast number of component/environment/usage combinations that may exist
Corrigan, P, Cole, I
core   +1 more source

Remaining useful life prediction of rotating equipment using covariate-based hazard models : Industry applications [PDF]

open access: yes, 2017
The ability to estimate the expected Remaining Useful Life (RUL) is critical to reduce maintenance costs, operational downtime and safety hazards. In most industries, reliability analysis is based on the Reliability Centred Maintenance (RCM) and lifetime
Yarlagadda, Prasad K.   +5 more
core   +1 more source

A New Cumulative Fatigue Damage Rule Based on Dynamic Residual S-N Curve and Material Memory Concept

open access: yesMetals, 2018
This paper introduces a new phenomenological cumulative damage rule to predict damage and fatigue life under variable amplitude loading. The rule combines a residual S-N curve approach and a material memory concept to describe the damage accumulation ...
Zhaochun Peng   +3 more
doaj   +1 more source

Postreproductive Life Predicted by Primate Patterns [PDF]

open access: yesThe Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 2000
Regression analyses of primate life spans on recently revised female body and brain masses of Old World primates predict a human life span of between 72 years and 91 years-estimates that exceed the age of human menopause (and prior estimates) by well over 20 years.
D S, Judge, J R, Carey
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

From Innovation to Standardization—A Century of Rolling Bearing Life Formula

open access: yesMachines
This review paper is an homage to Arvid Palmgren’s pioneering paper on rolling bearing service life to highlight its relevance a century later.
Tatjana Lazović   +4 more
doaj   +1 more source

Thermal Fatigue Modelling and Simulation of Flip Chip Component Solder Joints under Cyclic Thermal Loading

open access: yesEnergies, 2019
Thermal Fatigue of flip chip component solder joints is widely existing in thermal energy systems, which imposes a great challenge to operational safety.
Liangyu Wu   +4 more
doaj   +1 more source

The Study of the Reliability of Complex Components during the Electromigration Process

open access: yesMicromachines, 2023
With the increasing number of inputs and outputs, and the decreasing interconnection spacing, electrical interconnection failures caused by electromigration (EM) have attracted more and more attention.
Hao Cui   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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