Results 71 to 80 of about 679,610 (316)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
MODELLING OF STRESS GRADIENT EFFECT ON FATIGUE LIFE USING WEIBULL BASED DISTRIBUTION FUNCTION [PDF]
, 2013 In the present paper, a new approach is developed in order to take into account the stress gradient effect on fatigue life of structural components. The proposed approach is based on the weakest link concept in which the shape coefficient of the Weibull ...
PALIN-LUC, Thierry +2 more
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Fatigue life improvement in fatigue-aged fastener holes using the cold expansion technique [PDF]
, 2003 The use of cold expansion process as a life extension technique on aircraft structural joints was investigated. The primary focus was an experimental test programme consisting of open-hole and low-load transfer joint specimens made of 2024-T351 ...
Wang, Z., Zhang, Xiang
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
This chapter aims to provide an overview of the fatigue life prediction methods for composite materials and structures, recalling methods used in the past, discovering the present status and attempting to foresee future trends ...
Vassilopoulos, Anastasios
core +1 more source
Behavioural pattern identification and prediction in intelligent environments [PDF]
, 2013 In this paper, the application of soft computing techniques in prediction of an occupant's behaviour in an inhabited intelligent environment is addressed.
Mahmoud, S, Lotfi, A, Langensiepen, C
core +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
, 2006 A practical fatigue analysis methodology was developed for predicting the life of rotary-wing aircraft components. The focus of this fatigue capability was two-fold.
Cowell, Jason Michael
core
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source