Results 71 to 80 of about 8,942,242 (366)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
A Combined High and Low Cycle Fatigue Life Prediction Model for Wind Turbine Blades
Applied SciencesA novel method is proposed for a combined high and low cycle fatigue (CCF) life prediction model based on Miner’s rule, incorporating load interactions and coupled damage effects to evaluate the fatigue life of wind turbine blades under CCF loading.
Miaomiao Li +2 more
doaj +1 more source
Shiyou jixie, 2022 In order to analyze the oxygen corrosion of the pipe string under the nitrogen anti-soluble condition in the salt cavern underground gas storage and predict its service life, the high temperature and high pressure corrosion weight loss test was carried ...
Wan Liping +4 more
doaj
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
FE implementation of damage-coupled inelastic constitutive equation for P91 steel
Mechanical Engineering JournalThe objective of this study is to numerically evaluate the cyclic softening behavior and creep-fatigue damage of P91 steel. To achieve this, a damage-coupled inelastic constitutive equation is formulated by coupling the Chaboche-type viscoplastic ...
Masayuki ARAI, Akihiro MOTOKI
doaj +1 more source
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
EMUs Electrical Connector Life Prediction Based on Accelerated Degradation Data
机车电传动, 2019 The electrical connectors of EMUs play a very important role in train operation. In order to improve the efficiency and accuracy of life prediction of electrial connector products, the connector accelerated test was designed and implemented, and the ...
Jie MA +4 more
doaj
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Influence of axial load on internal pressure creep of Mod.9Cr-1Mo circumferential welded pipe
Nihon Kikai Gakkai ronbunshu, 2015 Mod.9Cr-1Mo steel(P91) is widely used for high temperature pipes in ultra-super-critical thermal power plants. However it was recently reported that the creep damage was detected at heat affected zone(HAZ) in welded joints of the pipes so-called the ...
Takashi OGATA +2 more
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source