Results 121 to 130 of about 8,218,819 (301)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
This year on the 10th of March, Dmytro Deonysovych Zerbino, clinical pathologist, who started to work at Lviv University in 1966, celebrated his 90th birthday. D.D. Zerbino – doctor of medical sciences (1965), professor (1966), honored man of science and
Dmytro Zerbino
doaj
Life science payloads planning study integration facility survey results [PDF]
The integration facility survey effort described is structured to examine the facility resources needed to conduct life science payload (LSP) integration checkout activities at NASA-JSC.
Brown, N. E. +2 more
core +1 more source
Fifteen Billion Years of Searching for God: Neither Science nor Theology Can Afford to Be Dogmatic [PDF]
This essay argues that, in the search for truth, the findings of both science and theology are provisional. The author makes a strong case for clergy to stay informed about current science and technology, so that they can challenge their congregations to
Kaplan, Daniel Lee
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Ambiguous Bodies, Biopower and the Ideologies of Science Fiction [PDF]
Contemporary Hollywood film narrates the fear of monstrous science; attending to the modulations of medicine, capital and the body. The filmic body is employed to illustrate the power of the new biotechnologies to create and sustain life and the new ...
Flynn, Susan
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source

