Results 141 to 150 of about 2,423,258 (261)

Context-based refinement of mappings in evolving life science ontologies. [PDF]

J Biomed Semantics, 2023
Yamamoto VE, Destro JM, Dos Reis JC.
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Case study: creating an 'AI for Academic Writing Skills' induction session for postgraduate life science courses. [PDF]

Emerg Top Life Sci
Carter J, Ferrey A, Lam H, Webb-Davies K, Young D, Zonta B, O' Rourke D.   +6 more
europepmc   +1 more source

Emerging Field-Effect Transistor Biosensors for Life Science Applications. [PDF]

Bioengineering (Basel), 2023
Panahi A, Ghafar-Zadeh E.
europepmc   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Highlighting Counterstereotypical Scientists in Undergraduate Life Science Courses. [PDF]

CBE Life Sci Educ
Costello RA, Ewell SN, Adams PE, Aranda ML, Curry A, De Jesus MM, Dunk RDP, García-Ojeda ME, Gutzler SJ, Habersham LRA, Kjelvik MK, Mateen M, Metzger KJ, Mulligan KX, Owens MT, Pigg RM, Quillin K, Rice MM, Sovi S, Schultheis EH, Schultz J, Theobald EJ, Tracey E, Tripp B, Yang S, Zemenick A, Ballen CJ, Ovid D.   +27 more
europepmc   +1 more source

Integrating supercomputing and artificial intelligence for life science. [PDF]

Patterns (N Y), 2022
Rao J, Zheng S, Yang Y.
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Turning data into insights in Jub, an extensible generic big data platform for life science and healthcare applications. [PDF]

Sci Rep
Castillo-Barrios I, Crespo-Sanchez M, Reyes-Anastacio HG, Gonzalez-Compean JL, Lopez-Arevalo I, Barron-Lugo JA, Morin-Garcia JC, Leal YA, Calderon-Hernandez J, Aguirre-Meneses H, Núñez-Gaona MA.   +10 more
europepmc   +1 more source

The effectiveness of Japanese public funding to generate emerging topics in life science and medicine. [PDF]

PLoS One, 2023
Ohniwa RL, Takeyasu K, Hibino A.
europepmc   +1 more source