Results 151 to 160 of about 2,415,203 (259)

Context-based refinement of mappings in evolving life science ontologies. [PDF]

J Biomed Semantics, 2023
Yamamoto VE, Destro JM, Dos Reis JC.
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Case study: creating an 'AI for Academic Writing Skills' induction session for postgraduate life science courses. [PDF]

Emerg Top Life Sci
Carter J, Ferrey A, Lam H, Webb-Davies K, Young D, Zonta B, O' Rourke D.   +6 more
europepmc   +1 more source

Emerging Field-Effect Transistor Biosensors for Life Science Applications. [PDF]

Bioengineering (Basel), 2023
Panahi A, Ghafar-Zadeh E.
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Highlighting Counterstereotypical Scientists in Undergraduate Life Science Courses. [PDF]

CBE Life Sci Educ
Costello RA, Ewell SN, Adams PE, Aranda ML, Curry A, De Jesus MM, Dunk RDP, García-Ojeda ME, Gutzler SJ, Habersham LRA, Kjelvik MK, Mateen M, Metzger KJ, Mulligan KX, Owens MT, Pigg RM, Quillin K, Rice MM, Sovi S, Schultheis EH, Schultz J, Theobald EJ, Tracey E, Tripp B, Yang S, Zemenick A, Ballen CJ, Ovid D.   +27 more
europepmc   +1 more source

Integrating supercomputing and artificial intelligence for life science. [PDF]

Patterns (N Y), 2022
Rao J, Zheng S, Yang Y.
europepmc   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Brilliant life in science

Інтродукція Рослин, 2006
T.M. Cherevchenko, S.V. Klimenko, N.M. Shyian, O.M. Tsarenko, P.E. Bulakh, O.V. Bulakh, L.I. Buyun, L.A. Kovalska, V.S. Vahrushkin   +8 more
doaj   +1 more source

Turning data into insights in Jub, an extensible generic big data platform for life science and healthcare applications. [PDF]

Sci Rep
Castillo-Barrios I, Crespo-Sanchez M, Reyes-Anastacio HG, Gonzalez-Compean JL, Lopez-Arevalo I, Barron-Lugo JA, Morin-Garcia JC, Leal YA, Calderon-Hernandez J, Aguirre-Meneses H, Núñez-Gaona MA.   +10 more
europepmc   +1 more source