Results 131 to 140 of about 8,218,819 (301)

Space Station Centrifuge: A Requirement for Life Science Research [PDF]

open access: yes
A centrifuge with the largest diameter that can be accommodated on Space Station Freedom is required to conduct life science research in the microgravity environment of space.
Fuller, Charles A.   +3 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

First International Microgravity Laboratory [PDF]

open access: yes
This colorful booklet presents capsule information on every aspect of the International Microgravity Laboratory (IML). As part of Spacelab, IML is divided into Life Science Experiments and Materials Science Experiments.
Accardi, Denise   +8 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

A LIFE IN SCIENCE WHICH IS LIFE ITSELF

open access: yesGeography, Environment, Sustainability, 2011
A LIFE IN SCIENCE WHICH IS LIFE ITSELFOn the 80th anniversary of Academician V.M ...
Arkady Tishkov
doaj  

A Life in Science [PDF]

open access: yesCBE—Life Sciences Education, 2011
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

God and the Gaps

open access: yes, 2013
Excerpt: Most often the story is told like this: There is some feature of the world that science is at a loss to explain. Christians rush to claim that this feature can only be explained by God.
McCullough, Ross W.
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

D.N. Zernov: life for science

open access: yesСеченовский вестник, 2014
At November, 9 in 2013 was 170 years since the birth of the great russian anatomist D.N. Zernov, the professor of anatomy of the Moscow University. In 1869 D.N.
A. I. Shvedavchenko   +2 more
doaj  

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