Results 131 to 140 of about 8,033,101 (355)

Life and Science [PDF]

open access: yesAnnual Review of Biochemistry, 1982
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Fifteen Billion Years of Searching for God: Neither Science nor Theology Can Afford to Be Dogmatic [PDF]

open access: yes, 2012
This essay argues that, in the search for truth, the findings of both science and theology are provisional. The author makes a strong case for clergy to stay informed about current science and technology, so that they can challenge their congregations to
Kaplan, Daniel Lee
core   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

open access: yesFEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

LIFE CREDO – SERVING SCIENCE

open access: yesПраці Наукового товариства імені Шевченка. Медичні науки, 2016
This year on the 10th of March, Dmytro Deonysovych Zerbino, clinical pathologist, who started to work at Lviv University in 1966, celebrated his 90th birthday. D.D. Zerbino – doctor of medical sciences (1965), professor (1966), honored man of science and
Dmytro Zerbino
doaj  

Life in 2050: Amazing Science, Familiar Threats [PDF]

open access: yes, 2010
Presents survey findings on expectations for developments in technology, medical research, war and terrorism, energy and the environment, race relations, health care, and the U.S.

core  

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

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