Results 141 to 150 of about 8,207,011 (340)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Life Science Payloads Planning Study Integration Facility Survey: Executive Summary [PDF]
Analyses of proposed life science shuttle era payload operations are discussed. A summary of results from a survey conducted to: (1) examine facility and equipment resources needed for life science payload integration, checkout, test and mission support ...
Brown, N. E., Wells, G. W.
core +1 more source
Life in 2050: Amazing Science, Familiar Threats [PDF]
, 2010 Presents survey findings on expectations for developments in technology, medical research, war and terrorism, energy and the environment, race relations, health care, and the U.S.
core
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
A LIFE IN SCIENCE WHICH IS LIFE ITSELF
Geography, Environment, Sustainability, 2011 A LIFE IN SCIENCE WHICH IS LIFE ITSELFOn the 80th anniversary of Academician V.M ...
Arkady Tishkov
doaj
Microgravity Particle Research on the Space Station [PDF]
Science questions that could be addressed by a Space Station Microgravity Particle Research Facility for studying small suspended particles were discussed. Characteristics of such a facility were determined.
Mckay, Christopher P. +2 more
core +1 more source
, 2015 Data Science---Today, everybody and everything produces data. People produce large amounts of data in social networks and in commercial transactions. Medical, corporate, and government databases continue to grow.
Plaat, Aske
core +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The science and culture of SETI: Life On Other Worlds: The 20th-Century Life Debate by Stephen J Dick, Cambridge University Press, 1998, ISBN 0 521 62012 0, 17.95 (hbk) [PDF]
, 1999 I. Crawford
openalex +1 more source