Results 171 to 180 of about 8,207,011 (340)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

ACADEMICIAN NIKOLAY VASILIEV: LIFE IN SCIENCE

Сибирский онкологический журнал, 2016
The article presents a biographical sketch of the outstanding Russian scientist, academician of RAMS, Professor N.V. Vasiliev.
Е. L. Choinzonov, N. V. Cherdyntseva, S. A. Nekrylov   +2 more
doaj  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Data science and data analytics in life science research

Artificial Intelligence in the Life Sciences, 2023
Jürgen Bajorath
doaj   +1 more source

Life in Science [PDF]

Bacteriophage, 2012
openaire   +2 more sources

PLOS Science Wednesday: Hi reddit, my name is Stefan Bengston and I recently found the world’s oldest plant-like fossil, which suggests multicellular life evolved much earlier than we previously thought – Ask Me Anything! [PDF]

, 2017
PLOSScienceWednesday, r Science
openalex   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Quantum Life Science: A Paradigm for Life Science Research. [PDF]

ACS Nano
Kono H, Yukawa H, Hiromoto T, Igarashi R, Takakusagi Y, Adachi M, Baba Y.   +6 more
europepmc   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Editorial: Micro/nano devices and technologies for neural science and medical applications

Frontiers in Bioengineering and Biotechnology
Juntao Liu, Zhugen Yang, Yang Wang, Li Wang, Ziyue Li   +4 more
doaj   +1 more source