Results 101 to 110 of about 2,264,386 (292)

Functional role and folding properties of the glucan‐binding domain of oral bacterial glucansucrase

open access: yesFEBS Letters, EarlyView.
The role of the glucan‐binding domain in Streptococcus sobrinus glucansucrase was examined, focusing on its impact on enzymatic activity, dextran binding, and structural stability of deletion mutants and a circularly permuted protein. Our research revealed that glucosyl transfer efficiency is linked to cooperative interdomain folding.
Hideyuki Komatsu   +5 more
wiley   +1 more source

Des bio-objets pour la bioéthique. Compte rendu de Bio-Objects: Life in the 21st Century

open access: yesBioéthiqueOnline, 2014
The collective work Bio-Objects: Life in the 21st Century, edited by Niki Vermeulen, Saka Tamminen and Andrew Webster analyzes new forms of life arising from the biosciences in terms of their bio-objectification.
Couture, Vincent
doaj  

Towards an Education Through and For Social Justice: Humanizing a Life Sciences Curriculum Through Co-Creation, Critical Thinking and Anti-Racist Pedagogy

open access: yesSocial Sciences
Degree awarding gaps highlight the inequitable outcomes of higher education (HE) for racially minoritized students in the UK. This ongoing issue has been described as a “wicked problem”, directly related to structural racism, or policies and practices ...
Amy Maclatchy   +4 more
doaj   +1 more source

The cytochrome oxidase defect in ISC‐depleted yeast is caused by impaired iron–sulfur cluster maturation of the mitoribosome assembly factor Rsm22

open access: yesFEBS Letters, EarlyView.
The yeast mitoribosome assembly factor Rsm22 contains a [4Fe‐4S] cluster that is matured by the mitochondrial iron–sulfur cluster assembly (ISC) machinery. Defects in ISC components result in impaired mitochondrial protein synthesis due to a mitoribosome assembly defect.
Ulrich Mühlenhoff   +4 more
wiley   +1 more source

Analysis of Student Dropout Risk in Higher Education Using Proportional Hazards Model and Based on Entry Characteristics

open access: yesData
The aim of this study is to identify the key factors contributing to student dropout and to develop a predictive model that estimates the dropout risk of students based on their entry characteristics and enrolment registration data. Our analysis is based
Liga Paura   +3 more
doaj   +1 more source

Development of visible light‐sensitive human neuropsin (OPN5) via single amino acid substitution

open access: yesFEBS Letters, EarlyView.
The present study determines a key amino acid residue, Lys91, for defining UV sensitivity of human OPN5. Heterologous action spectroscopy of the wild type and K91 mutants of OPN5 in HEK293T cells reveals that substitution of Lys91 with neutral (alanine) or acidic amino acids (glutamic or aspartic acids) causes substantial shifts in spectral sensitivity
Yusuke Sakai   +2 more
wiley   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

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