Results 131 to 140 of about 15,808,373 (394)

USSR Space Life Sciences Digest, issue 3 [PDF]

open access: yes
This is the third issue of NASA's USSR Space Life Sciences Digest. Abstracts are included for 46 Soviet periodical articles in 20 areas of aerospace medicine and space biology and published in Russian during the second third of 1985.
Garshnek, V.   +4 more
core   +2 more sources

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

New indicators and indexes for benchmarking university–industry–government innovation in medical and life science clusters: results from the European FP7 Regions of Knowledge HealthTIES project

open access: yesHealth Research Policy and Systems, 2019
Background While the European Union is striving to become the ‘Innovation Union’, there remains a lack of quantifiable indicators to compare and benchmark regional innovation clusters.
Laurel D. Edmunds   +21 more
doaj   +1 more source

Practical computational reproducibility in the life sciences

open access: yesbioRxiv, 2017
Many areas of research suffer from poor reproducibility. This problem is particularly acute in computationally intensive domains where results rely on a series of complex methodological decisions that are not well captured by traditional publication ...
Bjorn Gruning   +7 more
semanticscholar   +1 more source

Analogical Reflection as a Source for the Science of Life: Kant and the Possibility of the Biological Sciences [PDF]

open access: yes, 2016
In contrast to the previously widespread view that Kant's work was largely in dialogue with the physical sciences, recent scholarship has highlighted Kant's interest in and contributions to the life sciences.
Nassar, Dalia
core  

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Artificial Intelligence in Medicine: Preparing for the Confirmed Inevitable. Theoretical and Methodological Considerations [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2019
The AI in Medicine project began with a simple yet complex and multilevel question. In late 2017, prompted by direct experience of researching human-machine interchanges, we asked whether the traditional principles of interaction between a physician and ...
Andrey V. Rezaev, Piotr K. Yablonskiy
doaj  

Sources Of Student Engagement In Introductory Physics For Life Sciences [PDF]

open access: yes, 2018
We explore the sources of student engagement with curricular content in an Introductory Physics for Life Science (IPLS) course at Swarthmore College. Do IPLS students find some life-science contexts more interesting than others, and, if so, what are the ...
Crouch, Catherine Hirshfeld   +2 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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