Results 131 to 140 of about 2,956,560 (314)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
9th International Conference on Biosystems Engineering 2018 : Book of Abstracts : 9-11 May 2018
Full textBook of Abstracts. 9th International Conference on Biosystems Engineering 2018, May 9–11, 2018 Tartu, Estonia.
Estonian University of Life Sciences
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Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Ökosüsteemiteenuste ja nende mõju hindamine inimheaolule Harku valla linnalähedasel maastikul
A Thesis for applying for the degree of Doctor of Philosophy in Landscape Architecture.Väitekiri filosoofiadoktori kraadi taotlemiseks maastikuarhitektuuri erialal.ABSTRACT.
Nevzati, Fiona
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Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
XIII International Congress in Animal Hygiene, June 17-21, 2007, Tartu, Estonia "Animal health, animal welfare and biosecurity" : proceedings. Volume 1 [PDF]
KonverentsikogumikOn behalf of both the Organising Committee and the Scientific Committee, I am pleased to welcome you in Tartu, Estonia, to participate at the XIII International Congress of the International Society for Animal Hygiene (ISAH).
Estonian University of Life Sciences
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Thesaurus Ethics in the Life Sciences 3rd Edition
The project, which was initiated by the DRZE in 1999, brings together five partners who decided to pool their professional experience with various thesauri in order to create a new Thesaurus Ethics in the Life Sciences.
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