Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Thomas Aquinas, the Beginning of Human Life and the Science of the Soul
, 2016 Łukasz Dominiak
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USSR Space Life Sciences Digest, issue 8 [PDF]
This is the eighth issue of NASA's USSR Space Life Sciences Digest. It contains abstracts of 48 papers recently published in Russian language periodicals and bound collections and of 10 new Soviet monographs.
Hooke, L. R. +5 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Emergence of Romanian Life Sciences Clusters in the Context of the New EU Industrial Strategy
, 2021 Valentin Cojanu +2 more
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Acceptance of Biological Evolution by First-Year Life Sciences University Students [PDF]
, 2020 Lia Betti, Peter Shaw, Volker Behrends
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USSR Space Life Sciences Digest, issue 16 [PDF]
This is the sixteenth issue of NASA's USSR Life Sciences Digest. It contains abstracts of 57 papers published in Russian language periodicals or presented at conferences and of 2 new Soviet monographs.
Donaldson, P. Lynn +5 more
core +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Contribution of Information Science Technology to the Research on Systems Life Sciences.
, 2003 Masahiro Okamoto
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