Results 91 to 100 of about 8,829,421 (292)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Problem Based Learning (PBL)-Based Entrepreneurship Learning Model Development to Improve the Life Skills of the Teacher Training Students in Private Universities throughout Solo Raya [PDF]

open access: yes, 2012
Purpose – This research aims at providing a PBL-based Entrepreneurship learning model to improve the student life skills in Private Faculties of Teacher Training and Educationin Solo Raya.
Suryanti, Hera Heru Sri   +1 more
core  

Pembelajaran Fisika dengan Model Siklus Belajar 5-E (Engage, Explore, Explain, Elaborate, Evaluate) sebagai Upaya Meningkatkan Kecakapan Hidup Siswa

open access: yesJPFT (Jurnal Pendidikan Fisika dan Teknologi), 2017
Life skills of students and teachers in the Province of West Nusa Tenggara, especially the island of Lombok is still low. Development of life skills is not optimal attention of government and education observers.
Hikmawati Hikmawati
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

PALS – Play and Life Skills: Play as an Opportunity for Developing Life Skills

open access: yes
...
Weidinger, Wiltrud   +4 more
openaire   +2 more sources

Narrative Counseling and Life Skills

open access: yesEncyclopaideia : rivista di fenomenologia, pedagogia, formazione, 2009
con referee ...
openaire   +3 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Skills for Life strategy : 2005 - 2010 [PDF]

open access: yes, 2005
"The actions which Skills for Life providers in London West should undertake to widen participation and improve the quality of Skills for Life provision in the London West LSC area including the boroughs of Brent, Ealing, Hammersmith and Fulham, Harrow ...

core   +2 more sources

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