Results 81 to 90 of about 8,829,421 (292)

Skills At Work, 1986 to 2006 [PDF]

open access: yes, 2007
This report examines the skills used by British workers and highlights a significant increase in job skills over the last two decades, with computing and 'influencing' skills in particular growing in importance over the last five years.
Gallie, Duncan   +3 more
core  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

The multiple scarring effects of youth unemployment

open access: yes, 2015
Fundamentally for this paper, the disadvantages of youth unemployment may not be just temporary, but may have longer-term impacts. Considerable evidence suggests that being unemployed when young leads to a higher likelihood of long-term ‘scarring ...
McQuaid, Ronald
core   +1 more source

DEVELOPING LIFE SKILLS IN YOUTH

open access: yesInternational Journal of Research -GRANTHAALAYAH, 2016
Life skills help young people navigate the challenges of everyday life. They enable them to develop into healthy, responsible, and productive adults. Adolescent life skills are central to psychological theories that aim to understand how skills and competencies develop.
openaire   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Non-formal girls’ life skills programming Implications for policy and practice [PDF]

open access: yes, 2018
Research in developing countries demonstrates the importance of life skills for improving a range of outcomes for adolescent girls. These outcomes include improved psychosocial and mental health (e.g., emotional resilience, reduced post-traumatic stress,
Kwauk, Christina   +5 more
core  

Every child needs to learn these essential life skills

open access: yes, 2022
When we talk about life skills, what comes to mind? In the filed of psychology and child development, "adpative behaviour" and "executive function" are two terms that can be defined as essential like skills, especially for children who are still ...
Ng, Alvin Lai Oon *
core  

Relational aggression: the voices of primary school learners

open access: yesSouth African Journal of Education, 2014
The aim of this research was to explore and describe primary school learners' experiences of relational aggression at school. This was done within a qualitative research design with a phenomenological approach.
Johan Botha
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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