Results 141 to 150 of about 3,089,683 (304)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Editorial: Exploring life skills and positive youth development through sports. [PDF]

Front Sports Act Living
Muñoz-Llerena A, Hernández-Hernández E, Murta L, Lagunes-Carrasco JO.   +3 more
europepmc   +1 more source

Developing 21st Century Essential Life Skills: Supporting self-regulation in 3-4 year olds [PDF]

, 2019
Barbour, Laura
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Life skills evaluation in a kindergarten special education classroom. [PDF]

J Appl Behav Anal
Torelli JN, Snyder SK, Griffin ML, Hellemn MP, Cagliani RR, Morgan GA.   +5 more
europepmc   +1 more source

CARDIOPULMONARY RESUSCITATION TRAINING FOR MEDICAL STUDENTS IN ANESTHESIOLOGY ROTATION IN ARDABIL MEDICAL UNIVERSITY (IRAN) [PDF]

Objectives : Cardiopulmonary resuscitation (CPR) training for undergraduate medical students has been noted to be poor in the past. Attempts have been made The aim of this study is to determine effect of CPR training in the anesthetic ward to improve ...
انتظاری, مسعود, عیسی زاده فر, خاطره   +1 more
core  

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Social media's effect on sexual literacy and healthy life skills in young adults. [PDF]

BMC Public Health
Dülger H, Ada G, Dilcen HY, Bilişli Y.
europepmc   +1 more source

Defining Life Skills in health promotion at school: a scoping review. [PDF]

Front Public Health, 2023
Darlington-Bernard A, Salque C, Masson J, Darlington E, Carvalho GS, Carrouel F.   +5 more
europepmc   +1 more source