Results 91 to 100 of about 8,714,418 (337)

[Evaluation of factors affecting healthy life style behaviors and quality of life in patients with heart disease].

open access: yesAnadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2011
OBJECTIVE The aim of this cross-sectional study was to determine sociodemographic and disease related factors affecting the quality of life and life style behavior in patients with heart disease. METHODS Data are collected via information form, Healthy
Nilay Küçükberber   +2 more
semanticscholar   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Study Bugs do a poster presentation [PDF]

open access: yes, 2011
The poster describes the concepts behind, and the development of, a series of short films which deliver study skills information to students using an informal, imaginative and slightly quirky style.
Butler, Emma   +2 more
core   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

The impact of the national vaccination program on COVID-19 Infection Trends in Iran: An interrupted time series analysis [PDF]

open access: yesفصلنامه ابن سینا
Background and aims: Various methods have been employed globally to prevent the spread of COVID-19. However, the effectiveness of vaccination in reducing COVID-19 infections requires further investigation.
Kolsoom Alimohamadi   +2 more
doaj  

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Genetic, environmental and life-style factors associated with longevity. Protocol and response of the LONGECYL Study

open access: gold, 2022
Tomás Vega   +5 more
openalex   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

The Role of Histamine H1 and H4 Receptors in Atopic Dermatitis: From Basic Research to Clinical Study

open access: yesAllergology International, 2014
Histamine plays important roles in inflammation and nervous irritability in allergic disorders, including atopic dermatitis (AD). It has been shown to regulate the expression of pruritic factors, such as nerve growth factor and semaphorin 3A, in skin ...
Yusuke Ohsawa, Noriyasu Hirasawa
doaj   +1 more source

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