Results 91 to 100 of about 2,350,551 (305)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Life style and Parkinson's disease. [PDF]

J Neural Transm (Vienna), 2022
Reichmann H, Csoti I, Koschel J, Lorenzl S, Schrader C, Winkler J, Wüllner U.   +6 more
europepmc   +1 more source

3. Edmund Burke and Conservatism

, 1958
Edmund Buxke (1729-1797) has often been compared to John Wesley, and there are several bases for such a comparison. Both infused a new life and meaning into the coin temporary formal structure of politics and religion, respectively.
Bloom, Robert L., Crapster, Basil L., Dunkelberger, Harold A., Glatfelter, Charles H., Mara, Richard T., Richardson, Norman E., Schubart, W. Richard   +6 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Investigation of the Combined Effects of workplace physical agents and shift work on Physiological parameters and blood factors in nurses

International Journal of Occupational Hygiene, 2022
Since nurses spend most of their working time indoors, the quality of the hospital environment has a great impact on their performance and comfort. The aim of this study was to investigate the combined effects of physical factors in the workplace and ...
keivan saedpanah, Mohammad Ghasemi, Hesam Akbari, Amir Adibzadeh, Hamed Akbari   +4 more
doaj  

A cross-sectional study on adherence to treatment and life-style modifications in hypertensive patients attending the urban health centre of a teaching hospital in Hyderabad. [PDF]

J Family Med Prim Care, 2023
Varma P, Mohandas A, Ravulapalli P, Pattnaik S, Varaprasad KS.   +4 more
europepmc   +1 more source

HOUSING MODEL AND URBAN LIFE STYLE [PDF]

, 2006
Joint Research on Environmental Science and Technology for the ...
Vu, Hao Quang
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Sprayable gelatin microparticles prevent delayed gastric bleeding in an anticoagulated swine model

Scientific Reports
Delayed bleeding following endoscopic mucosal resection or endoscopic submucosal dissection is a serious concern in patients receiving anticoagulant therapy.
Shohei Uehara, Fumisato Sasaki, Hidehito Maeda, Makoto Hinokuchi, Akihito Tanaka, Shiho Arima, Shinichi Hashimoto, Shuji Kanmura, Hisashi Sahara, Yasuko Kobayashi, Akihiro Nishiguchi, Tetsushi Taguchi   +11 more
doaj   +1 more source