Results 131 to 140 of about 2,350,551 (305)

Investigating Depression Literacy in Military Adults of Mashhad [PDF]

open access: yesPayesh
Objective(s): Depression literacy is an important concept and having adequate depression literacy can improve prevention, early diagnosis, intervention, and prognosis of depression.
Mohamad Ebrahimi   +4 more
doaj  

The effect of probiotic-fortified kefir on cardiovascular risk factors in elderly population: a double-blind, randomized, placebo-controlled clinical trial

open access: yesBMC Nutrition
Introduction The outbreak of cardiovascular disease (CVD) augments with age. Gut dysbiosis can worsen or initiate systemic disorders such as metabolic diseases and CVDs.
Mehran Noori   +7 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Occupational life-style programme over 12 months and changes of metabolic risk profile, vascular function, and physical fitness in blue-collar workers. [PDF]

open access: yesJ Occup Med Toxicol, 2023
Schaller N   +9 more
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Impact of covid-19 on education, psychological wellness and life style of dental students in Saudi Arabia. [PDF]

open access: yesBioinformation, 2022
Abdul NS   +5 more
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Applying the Social Cognitive Theory to Design a Health Education Program on Weight‐Loss Behaviors Among Police Officers: A Randomized Controlled Trial

open access: yesObesity Science & Practice
Background Being overweight/having obesity is a prevalent condition not only among the general population but also among individuals with special occupations such as police officers, where fitness is often a necessity.
Mohsen Saffari   +6 more
doaj   +1 more source

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