Results 191 to 200 of about 2,161,779 (334)

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Epidemiological, life style, and occupational factors associated with lower limb varicose veins: a case control study. [PDF]

open access: yesJ Egypt Public Health Assoc, 2021
Elamrawy S   +4 more
europepmc   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

open access: yesMolecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Evolution of the fungal self-fertile reproductive life style from self-sterile ancestors

open access: green, 1999
Sung‐Hwan Yun   +3 more
openalex   +1 more source

THE DETERMINANTS OF CRIMINAL VICTIMIZATION IN SÃO PAULO STATE [PDF]

open access: yes
In this paper an exploratory research of the determinants of criminal victimization in São Paulo state is conducted using the life-style and opportunity models with Seade's 1998 Pesquisa de Condição de Vida (Life Condition Survey).
Fábio Augusto Reis Gomes   +1 more
core  

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

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