Results 121 to 130 of about 6,730,594 (397)
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
End-of-life priorities of older adults with terminal illness and caregivers: A qualitative consultation [PDF]
, 2019 Background As older adults approach the end‐of‐life (EOL), many are faced with complex decisions including whether to use medical advances to prolong life. Limited information exists on the priorities of older adults at the EOL.
Barr, Margo +9 more
core +1 more source
Clinical Epidemiology and Global HealthAim and objectives: To determine the triggers for palliative care consultation (PCC) in non-malignant mechanically ventilated (MV) patients admitted to intensive care unit (ICU) and factors affecting modalities of palliative care (PC) delivery.
Mansi Suresh +3 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Revista Brasileira de Terapia IntensivaRESUMO Objetivo: Estimar a incidência de limitação de Suporte Avançado de Vida em pacientes graves internados em unidade de terapia intensiva com cuidados paliativos integrados.
Sandra Regina Gonzaga Mazutti +2 more
doaj +1 more source
O-15 Making end of life planning accessible – evaluating talking mats to support advance care planning with people living with neurological conditions [PDF]
, 2023 Sally Boa, Lois Cameron, Julie Mardon
openalex +1 more source
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Psychosocial support to families of people with severe and prolonged mental illness
INFAD, 2014 Family quality of life is affected when one member shows high support needs. Variables such as social support and sense of coherence appear to mediate the impact of care on quality of life.
Mª del Carmen García Pérez +3 more
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source