Results 61 to 70 of about 4,532,791 (345)

Dendritic cells steering antigen and leukocyte traffic in lymph nodes

FEBS Letters, EarlyView.
Dendritic cells are key players in the activation of T cells and their commitment to effector function. In this In a Nutshell Review, we will discuss how dendritic cells guide the trafficking of antigen and leukocytes in the lymph node, thus influencing T‐cell activation processes. Dendritic cells (DCs) play a central role in initiating and shaping the
Enrico Dotta, Agnieszka Katarzyna Maciola, Tania Baccega, Giulia Pasqual   +3 more
wiley   +1 more source

Part 11: Pediatric Basic Life Support and Cardiopulmonary Resuscitation Quality: 2015 American Heart Association Guidelines Update for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.

Circulation, 2015
This 2015 American Heart Association (AHA) Guidelines Update for Cardiopulmonary Resuscitation (CPR) and Emergency Cardiovascular Care (ECC) section on pediatric basic life support (BLS) differs substantially from previous versions of the AHA Guidelines ...
D. Atkins, S. Berger, J. Duff, John C Gonzales, E. Hunt, B. Joyner, P. Meaney, D. Niles, R. Samson, S. Schexnayder   +9 more
semanticscholar   +1 more source

Extracorporeal Life Support Organization (ELSO): 2020 Pediatric Respiratory ELSO Guideline.

ASAIO journal (1992), 2020
DISCLAIMER This guideline describes prolonged extracorporeal life support (ECLS) and extracorporeal membrane oxygenation (ECMO), applicable to Pediatric respiratory failure.
C. Maratta, Renee M. Potera, G. van Leeuwen, Andrés Castillo Moya, Lakshmi Raman, G. Annich, T. Brogan, M. Davidson, G. MacLaren, G. Peek   +9 more
semanticscholar   +1 more source

The dual nature of TDC – bridging dendritic and T cells in immunity

FEBS Letters, EarlyView.
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley   +1 more source

Uncovering critical transitions and molecule mechanisms in disease progressions using Gaussian graphical optimal transport

Communications Biology
Understanding disease progression is crucial for detecting critical transitions and finding trigger molecules, facilitating early diagnosis interventions. However, the high dimensionality of data and the lack of aligned samples across disease stages have
Wenbo Hua, Ruixia Cui, Heran Yang, Jingyao Zhang, Chang Liu, Jian Sun   +5 more
doaj   +1 more source

Preventative tele-health supported services for early stage chronic obstructive pulmonary disease: a protocol for a pragmatic randomized controlled trial pilot [PDF]

, 2011
Background Chronic Obstructive Pulmonary Disease (COPD) is a prevalent debilitating long term condition. It is the second most common cause of emergency admission to hospital in the UK and remains one of the most costly conditions to treat through ...
D Altman, Deborah A Fitzsimmons, Gail A Mountain, H Florence Sueng Kim, H Pinnock, Jill Thompson, Mark Hawley, R Meldrum   +7 more
core   +4 more sources

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source

Cervical collars and immobilisation: A South African best practice recommendation

African Journal of Emergency Medicine, 2017
Introduction: The consequences of spinal injury as a result of trauma can be devastating. Spinal immobilisation using hard trauma boards and rigid cervical collars has traditionally been the standard response to suspected spinal injury patients even ...
D. Stanton, T. Hardcastle, D. Muhlbauer, D. van Zyl   +3 more
doaj   +1 more source

End of Life Care: Achieving Quality in Hostels and for Homeless People, A Route to Success [PDF]

, 2010
This publication aims to provide a practical guide to support hostel staff in ensuring that people nearing the end of their life receive high quality end of life ...

core  

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source