Results 171 to 180 of about 861,553 (308)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
U.S. decennial life tables for 1999\u20132001, State Life Tables
Objective\u2014This report, following publication of the national life tables (1,2) for 1999\u20132001, presents state-specific life tables for the 50 states and District of Columbia by race (white and black) and sex.
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United States life tables eliminating certain causes of death, 1999-2001 [PDF]
Objectives: This report presents abridged cause-elimination life tables and multiple-decrement life table functions for 33 selected causes of death, by race (white and black) and sex, for the total United States. It is the fourth in a set of reports that
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Multiple decrement life tables of Cephus cinctus Norton (Hymenoptera: Cephidae) across a set of barley cultivars: The importance of plant defense versus cannibalism. [PDF]
PLoS One, 2020 Achhami BB +4 more
europepmc +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
United States life tables, 2020 [PDF]
Objectives\u2014This report presents complete period life tables for the United States by Hispanic origin, race, and sex, based on age-specific death rates in 2020.Methods\u2014Data used to prepare the 2020 life tables are 2020 final mortality statistics;
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Race adjustment hides and perpetuates systemic racism: real-world example using life tables. [PDF]
Am J EpidemiolRanapurwala SI +4 more
europepmc +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
U.S. state life tables, 2020 [PDF]
Objectives\u2014This report presents complete period life tables for each of the 50 states and the District of Columbia (D.C.) by sex based on age-specific death rates in 2020.Methods\u2014Data used to prepare the 2020 state-specific life tables include:
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