The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Race adjustment hides and perpetuates systemic racism: real-world example using life tables. [PDF]
Am J EpidemiolRanapurwala SI +4 more
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
U.S. decennial life tables for 1999\u20132001, State Life Tables
Objective\u2014This report, following publication of the national life tables (1,2) for 1999\u20132001, presents state-specific life tables for the 50 states and District of Columbia by race (white and black) and sex.
core
qlifetable: An R package for constructing quarterly life tables. [PDF]
PLoS OnePavía JM, Lledó J.
europepmc +1 more source
Influence of Temperature on Age-Stage, Two-Sex Life Tables for a Minnesota-Acclimated Population of the Brown Marmorated Stink Bug (Halyomorpha halys). [PDF]
Insects, 2020 Govindan BN, Hutchison WD.
europepmc +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
The crossover between life expectancies at birth and at age one: The imbalance in the life table [PDF]
The single most used demographic measure to describe population health is life expectancy at birth, but life expectancies at ages other than zero are also used in the study of human longevity.
Stan Becker, Vladimir Canudas-Romo
core
PopMortGen-India: an excel based tool for preparing population mortality files from life tables for relative survival analysis for cancer patients from India. [PDF]
EcancermedicalscienceDas DK, Tandale SR, Budukh AM.
europepmc +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source