Results 141 to 150 of about 861,553 (308)
A Dynamic Extension of the Period Life Table [PDF]
The standard period life table is based entirely on the death probabilities of the given period. Popular (not expert) usage of life expectancies from a period table typically ignores the fact that the expectancies make no allowance for future declines in
Byron G Spencer, Frank T Denton
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
United States life tables by Hispanic origin [PDF]
"Objectives: This report presents complete period life tables by Hispanic origin, race for the non-Hispanic white and non-Hispanic black populations, and sex for the United States based on age-specific death rates in 2006.
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
United States life tables,\ua01998
The life tables in this report are current life tables for the United States based on age-specific death rates in 1998. Data used to prepare these life tables are 1998 final mortality statistics; July 1, 1998, population estimates; and data from the ...
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The crossover between life expectancies at birth and at age one: The imbalance in the life table [PDF]
The single most used demographic measure to describe population health is life expectancy at birth, but life expectancies at ages other than zero are also used in the study of human longevity.
Stan Becker, Vladimir Canudas-Romo
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Life tables for the geographic divisions of the United States : 1959-61 [PDF]
This report contains the 1959-61 life tables for the nine geographic divisions of the United States. Separate life tables are presented by color and sex for each geographic division\u2014a total of 36 tables.These tables are based on the 1960 Census of ...
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Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source