Results 151 to 160 of about 7,945,921 (258)

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

United States life tables by Hispanic origin [PDF]

open access: yes
"Objectives: This report presents complete period life tables by Hispanic origin, race for the non-Hispanic white and non-Hispanic black populations, and sex for the United States based on age-specific death rates in 2006.

core  

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Life expectancy is the death-weighted average of the reciprocal of the survival-specific force of mortality [PDF]

open access: yes
The hazard of mortality is usually presented as a function of age, but can be defined as a function of the fraction of survivors. This definition enables us to derive new relationships for life expectancy.
Joel E. Cohen
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Tables of Racah coefficients

open access: yes, 1965
Tables of Racah Coefficients presents a compilation of tables of Racah coefficients. Racah coefficients appear and are widely used in a number of problems in quantum mechanics; in the theory of spectra of complex atoms and nuclei; in the theory of ...
Nikiforov, Arnol'd F. 1930-   +2 more
core  

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