Results 131 to 140 of about 14,125,984 (386)
The rate of telomere loss is related to maximum lifespan in birds
Telomeres are highly conserved regions of DNA that protect the ends of linear chromosomes. The loss of telomeres can signal an irreversible change to a cell's state, including cellular senescence.
Gianna M Tricola+25 more
semanticscholar +1 more source
Metabolic Consequences of Rheumatoid Arthritis
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry+2 more
wiley +1 more source
Background Global but predictable changes impact the DNA methylome as we age, acting as a type of molecular clock. This clock can be hastened by conditions that decrease lifespan, raising the question of whether it can also be slowed, for example, by ...
Tina Wang+9 more
doaj +1 more source
Adaptation, stress, and coping in sport [PDF]
Adaptation, which was mentioned within the domain of stress and coping research by Lazarus (1991), refers to the way in which people change according to the world that they live in.
Nicholls, Adam
core +1 more source
Ageism in Rheumatology: the Healthcare Professional's Perspective
Objective Ageism (age‐based stereotypes, prejudice, or discrimination) is prevalent and linked to prolonged disability and reduced lifespan in older adults. Little is known about ageism within rheumatology. This study explores the healthcare professional's (HCP) perception of the care of older adults and how ageist attitudes or perspectives may impact ...
Aaron P. Smith+4 more
wiley +1 more source
Chromatin, which organizes DNA, changes its structure to adapt to stress like high oxygen levels (hyperoxia), which can damage cells. Researchers developed a technique to observe these changes and found variability in how different parts of chromatin remodel.
Lauren Monroe+4 more
wiley +1 more source
The threshold age of Keyfitz' entropy [PDF]
BACKGROUND Indicators of relative inequality of lifespans are important because they capture the dimensionless shape of aging. They are markers of inequality at the population level and express the uncertainty at the time of death at the individual level. In particular, Keyfitz' entropy $\bar{H}$ represents the elasticity of life expectancy to a change
arxiv
Limited Lifespan vs. Perpetuity: Foundation Survey [PDF]
Survey gathering information about characteristics of foundations existing in perpetuity vs. foundations with a limited lifespan.
core
Openness to Experience and Culture-Openness Transactions Across the Lifespan
We examined the life span development of openness to experience and tested whether change in this personality trait was associated with change in cultural activity, such as attending the opera or visiting museums.
T. Schwaba+4 more
semanticscholar +1 more source
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi+4 more
wiley +1 more source