Results 111 to 120 of about 467,497 (301)

Blowup of small data solutions for a quasilinear wave equation in two space dimensions

open access: yes, 1998
For the quasilinear wave equation \partial_t^2u - \Delta u = u_t u_{tt}, we analyze the long-time behavior of classical solutions with small (not rotationally invariant) data.
Alinhac, Serge
core  

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi   +8 more
wiley   +1 more source

Carbon loss by deciduous trees in a CO2-rich ancient polar environment [PDF]

open access: yes, 2003
Fossils demonstrate that deciduous forests covered the polar regions for much of the past 250 million years 1 when the climate was warm and atmospheric CO2 high 2.
Beerling, D.J.   +2 more
core  

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

Demographic factors impact the rate of hearing decline across the adult lifespan

open access: yesCommunications Medicine
Background Little is known about the natural history of hearing loss in adults, despite it being an important public health problem. The purpose of this study is to describe the rate of hearing change per year over the adult lifespan.
Lauren K. Dillard   +4 more
doaj   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone   +8 more
wiley   +1 more source

Female thermal sensitivity and behaviour across the lifespan: A unique journey

open access: yesExperimental Physiology
Women are a group of individuals that undergo unique anatomical, physiological and hormonal changes across the lifespan. For example, consider the impact of the menstrual cycle, pregnancy and menopause, all of which are accompanied by both short‐ and ...
Davide Filingeri   +2 more
doaj   +1 more source

Moisture content analysis of wooden bridges [PDF]

open access: yes, 2019
The article deals with assessing the impact of moisture content conditions in wood mass of the wood bridges constructions on their lifespan in Central Europe.
Fojtík, Roman
core  

Prognostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in ALD‐Related Myelopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak   +4 more
wiley   +1 more source

Beyond Five Percent: The New Foundation Payout Menu [PDF]

open access: yes, 2007
Looks at thirteen foundations and examines the ways in which their non-standard structures -- whether in the areas of lifespan, payout, or methods -- arise from their missions. Foundations can have an impact when they choose to increase their payout rate
Heidi Waleson
core  

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