Results 41 to 50 of about 713,516 (268)

Genes, lifestyles and obesity [PDF]

International Journal of Obesity, 2004
To review the role of genes and lifestyle factors, particularly dietary habits and physical activity patterns, in obesity risk as well as their potential interactions.A descriptive report of a number of genes definitely ascribed or potentially implicated in excessive fat accumulation leading to obesity as assessed by different research approaches ...
Marti, A., Moreno-Aliaga, M.J., Hebebrand, Johannes, Martínez, J.A.   +3 more
openaire   +2 more sources

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Health-related quality of life in children under treatment for overweight, obesity or severe obesity: a cross-sectional study in the Netherlands

BMC Pediatrics, 2023
Background It is unknown whether weight class is associated with impairment of health-related quality of life (HRQOL) for children in the Netherlands. The aim of this study was to explore generic and weight-specific HRQOL in a clinical cohort of children
Bibian van der Voorn, R. Camfferman, J. C. Seidell, J. Halberstadt   +3 more
doaj   +1 more source

“Strength gains in different age groups of overweight/obese adults: A pilot uncontrolled study”

Cogent Social Sciences, 2022
Controlled studies demonstrate that it is possible to improve muscle strength in people of all ages, including older populations. Clinically, it is relevant to establish whether a resistance training program (26 sessions of 60 minutes of aerobic workout ...
Roberto Pippi, Laura Moretti, Claudia Carnevali, Luca Tingoli, Antonella Settequattrini, Cristina Fatone, Chiara Perrone, Elisa Reginato, Pierpaolo De Feo, Carmine G. Fanelli   +9 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Impact of early and late morning supervised blood flow restriction training on body composition and skeletal muscle performance in older inactive adults

Translational Exercise Biomedicine
To investigate the impact of a supervised blood-flow restriction (BFR) training program performed at different times of the morning on body composition and muscle performance in older, inactive adults.
Peskett Logan E., Thomson Amy M., Arnason Julia K., Paudel Yadab, Sénéchal Martin   +4 more
doaj   +1 more source

The Obligate Intracellular Lifestyle [PDF]

Frontiers in Microbiology, 2011
Obligate intracellular bacteria represent consummate parasites, often covertly co-opting host resources to enable development and ultimately transmission to a new host. The overall success of this survival strategy is doubtless derived from co-evolution with respective eukaryotic hosts over hundreds of millions of years.
Fields, Kenneth A, Heinzen, Robert A, Carabeo, Rey   +2 more
openaire   +4 more sources

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Talking with pediatric patients with overweight or obesity and their parents: self-rated self-efficacy and perceived barriers of Dutch healthcare professionals from seven disciplines

BMC Health Services Research, 2022
Background Many healthcare professionals (HCPs) feel uncomfortable and incompetent talking about weight with children with overweight and obesity and their parents. To optimally target interventions that can improve obesity care for children, we assessed
B. van der Voorn, R. Camfferman, J. C. Seidell, J. Halberstadt   +3 more
doaj   +1 more source