Results 51 to 60 of about 1,150,597 (304)

Increasing response rates to lifestyle surveys: a pragmatic evidence review [PDF]

, 2011
Aims: Lifestyle surveys are often a key component of a local Joint Strategic Needs Assessment (JSNA), undertaken to inform public health planning. They are usually administered to a large number of people in order to provide a comprehensive profile of ...
S. McCluskey, Topping, A. E., Topping, Annie, McCluskey, S., McCluskey, Serena, Topping, AE; id_orcid, McCluskey, S, AE Topping   +7 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Adolescents’ healthy lifestyle

Jornal de Pediatria (Versão em Português), 2020
Using a wide and representative sample of adolescents from 37 countries, this study aimed to analyze how age changes adolescents' healthy lifestyle.The study included 148,839 adolescents who participated in the Health Behavior in School-aged Children 2010 survey.
Adilson Marques, Nuno Loureiro, Bruno Avelar-Rosa, Ana Naia, Margarida Gaspar de Matos   +4 more
openaire   +8 more sources

Digitaalisen markkinoinnin strategia Pure Lifestyle -verkkokaupalle [PDF]

, 2022
Tämä opinnäytetyö on luonteeltaan toiminnallinen ja se on toteutettu toimeksiantona suomalaiselle mikroyritys Pure Lifestyle Finland Oy:n verkkokaupalle nimeltään Pure Lifestyle.
Nyblom, Inka
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Genes, lifestyles and obesity [PDF]

International Journal of Obesity, 2004
To review the role of genes and lifestyle factors, particularly dietary habits and physical activity patterns, in obesity risk as well as their potential interactions.A descriptive report of a number of genes definitely ascribed or potentially implicated in excessive fat accumulation leading to obesity as assessed by different research approaches ...
Marti, A., Moreno-Aliaga, M.J., Hebebrand, Johannes, Martínez, J.A.   +3 more
openaire   +2 more sources

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

The Obligate Intracellular Lifestyle [PDF]

Frontiers in Microbiology, 2011
Obligate intracellular bacteria represent consummate parasites, often covertly co-opting host resources to enable development and ultimately transmission to a new host. The overall success of this survival strategy is doubtless derived from co-evolution with respective eukaryotic hosts over hundreds of millions of years.
Fields, Kenneth A, Heinzen, Robert A, Carabeo, Rey   +2 more
openaire   +4 more sources

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Health-related quality of life in children under treatment for overweight, obesity or severe obesity: a cross-sectional study in the Netherlands

BMC Pediatrics, 2023
Background It is unknown whether weight class is associated with impairment of health-related quality of life (HRQOL) for children in the Netherlands. The aim of this study was to explore generic and weight-specific HRQOL in a clinical cohort of children
Bibian van der Voorn, R. Camfferman, J. C. Seidell, J. Halberstadt   +3 more
doaj   +1 more source