Results 51 to 60 of about 554,191 (264)
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Detecting Trace Amounts of Narcotics in Serum by Delayed Luminescence
This paper was designed to test the feasibility of optical identification of trace amounts of narcotics in serum using photoinduced delayed luminescence (DL).
Yan Wang +5 more
doaj +1 more source
Genetics of Lifetime Reproductive Performance in Italian Heavy Draught Horse Mares
Our aims were to find a phenotypic variable to express mares’ lifetime reproductive performance after 6 breeding seasons (BS) in Italian Heavy Draught Horse breed (IHDH), and to estimate its heritability.
Roberto Mantovani +4 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Surface texturing is vital for enhancing light absorption and optimizing the optoelectronic properties of multicrystalline silicon (mc-Si) samples. Texturing significantly improves light absorption by minimizing reflectance and extending the effective ...
Karim Choubani +6 more
doaj +1 more source
Underwater Wireless Sensor Networks: Estimation of Acoustic Channel in Shallow Water
Underwater sensor networks (UWSN) include a large number of devices and sensors which are positioned in a specific area to carry out monitoring in cooperation with each other as well as data collection. In this paper it has been studied and simulated the
Elma Zanaj +4 more
doaj +1 more source
Measurement of the D± lifetime [PDF]
We report precise measurement of the Ds meson lifetime. The data were taken by the SELEX experiment (E781) spectrometer using 600 GeV/c Sigma-, pi- and p beams. The measurement has been done using 918 reconstructed Ds. The lifetime of the Ds is measured to be 472.5 +- 17.2 +- 6.6 fs, using K*(892)0K+- and phi pi+- decay modes.
M Iori +104 more
openaire +4 more sources
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Background Chimeric antigen receptor (CAR) T‐cell therapy has revolutionized the treatment of hematological malignancies, offering durable remissions. However, concerns regarding its neurocognitive and psychological impact have emerged, particularly in ...
Ashvath Arumugam Pillai +11 more
doaj +1 more source

