Results 31 to 40 of about 554,191 (264)

Persistence with topical glaucoma therapy in Japan from the perspective of product, formulation, and patient characteristics: analysis of medical insurance claim data

BMC Ophthalmology
Background Glaucoma is the leading cause of irreversible blindness in Japan and constitutes a serious public health challenge. Due to its asymptomatic onset and slow progression, patient persistence with topical glaucoma therapies remains low ...
Kenji Kabeya, Hiroki Satoh, Natsuyo Yanagi, Yasufumi Sawada   +3 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Instillation success rates among glaucoma eyedrop products: patient survey in Japan

BMC Ophthalmology
Background Glaucoma is the leading cause of blindness in Japan and poses a significant public health challenge. Previous studies have reported low success rates for antiglaucoma eyedrop instillation.
Kenji Kabeya, Hiroki Satoh, Natsuyo Yanagi, Yasufumi Sawada   +3 more
doaj   +1 more source

Measuring lifetime poverty [PDF]

Journal of Economic Theory, 2011
The paper provides an axiomatic framework necessary to investigate the lifetime poverty for an individual as well as for the society, and to identify the appropriate axioms for their measurement. It further suggests that consumption rather than income is a more accurate measurement of the standard of living over time, especially in the context of ...
Michael Hoy, Buhong Zheng
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Quantifying benefits of renewable investments for German residential Prosumers in times of volatile energy markets

Nature Communications
The COVID-19 pandemic and the Russian invasion of Ukraine have led to unseen disruptions in the global energy markets since the end of 2021. Residential renewable investments like photovoltaic systems, battery home storage systems, and heat pumps are ...
Jonas van Ouwerkerk, Mauricio Celi Cortés, Najet Nsir, Jingyu Gong, Jan Figgener, Sebastian Zurmühlen, Christian Bußar, Dirk Uwe Sauer   +7 more
doaj   +1 more source

A measurement of the KS lifetime [PDF]

Physics Letters B, 1987
12 pages, 1 figure, to be published in Physics Letters ...
LAI A, MARRAS D, BATLEY JR, BEVAN A, DOSANJH RS, GERSHON TJ, HAY B, KALMUS GE, LAZZERONI C, MUNDAY DJ, NEEDHAM MD, OLAIYA E, PARKER MA, WHITE TO, WOTTON SA, BARR G, BOCQUET G, CECCUCCI A, CUHADAR DONSZELMANN T, CUNDY D, D'AGOSTINI G, DOBLE N, FALALEEV V, FUNK W, GATIGNON L, GONIDEC A, GORINI B, GOVI G, GRAFSTROM P, KUBISCHTA W, LACOURT A, LENTI M, LUITZ S, MATHEYS JP, MIKULEC I, NORTON A, PALESTINI S, PANZER STEINDEL B, SCHINZEL D, TATISHVILI G, TAUREG H, VELASCO M, VOSSNACK O, WAHL H, CHESHKOV C, GAPONENKO A, HRISTOV P, KEKELIDZE V, MADIGOJINE D, MOLOKANOVA N, POTREBENIKOV Y, TKATCHEV A, ZINCHENKO A, KNOWLES I, MARTIN V, PARSONS H, SACCO R, WALKER A, CONTALBRIGO, Marco, DALPIAZ, Pietro, DUCLOS J, FRABETTI PL, GIANOLI, Alberto, MARTINI, Mara, PETRUCCI, Ferruccio Carlo, SAVRIE', Mauro, SCARPA, MARCELLA, BIZZETI A, CALVETTI M, COLLAZUOL G, GRAZIANI G, IACOPINI E, MARTELLI F, VELTRI M, BECKER HG, BLUMER H, COWARD D, EPPARD M, FOX H, HIRSTIUS A, HOLTZ K, KALTER A, KLEINKNECHT K, KOCH U, KOPKE L, DA SILVA PL, MAROUELLI P, PELLMANN I, PETERS A, SCHMIDT SA, SCHONHARTING V, SCHUE Y, WANKE R, WINHART A, WITTGEN M, CHOLLET JC, CREPE S, FAYARD L, ICONOMIDOU FAYARD L, OCARIZ J, UNAL G, WINGERTER SEEZ I, ANZIVINO G, CENCI P, IMBERGAMO E, LUBRANO P, MESTVIRISHVILI A, NAPPI A, PEPE M, PICCINI M, BERTANZA L, BIGI A, CALAFIURA P, CAROSI R, CASALI R, CERRI C, CIRILLI M, COSTANTINI F, FANTECHI R, GIUDICI S, MANNELLI I, PIERAZZINI G, SOZZI M, CHEZE JB, COGAN J, DE BEER M, DEBU P, DERUE F, FORMICA A, DE CASSAGNAC RG, MAZZUCATO E, PEYAUD B, TURLAY R, VALLAGE B, AUGUSTIN I, BENDER M, HOLDER M, MAIER A, ZIOLKOWSKI M, ARCIDIACONO R, BIINO C, CARTIGLIA N, GUIDA R, MARCHETTO F, MENICHETTI E, PASTRONE N, NASSALSKI J, RONDIO E, SZLEPER M, WISLICKI W, WRONKA S, DIBON H, FISCHER G, JEITLER M, MARKYTAN M, NEUHOFER G, PERNICKA M, TAUROK A, WIDHALM L, CA NA48 COLLABORATION   +159 more
openaire   +7 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

QTSAC: An Energy-Efficient MAC Protocol for Delay Minimization in Wireless Sensor Networks

IEEE Access, 2018
Millions of sensors are deployed to monitor the smart grid. They consume huge amounts of energy in the communication infrastructure. Therefore, the establishment of an energy-efficient medium access control (MAC) protocol for sensor nodes is challenging ...
Yuxin Liu, Kaoru Ota, Kuan Zhang, Ming Ma, Naixue Xiong, Anfeng Liu, Jun Long   +6 more
doaj   +1 more source