Results 41 to 50 of about 2,314,111 (354)

Bisphosphonate compliance in Japan from the perspective of product, formulation, and patient characteristics: analysis of medical insurance claim data

Journal of Pharmaceutical Health Care and Sciences
Background Bisphosphonates are the mainstay drugs for osteoporosis, but in clinical practice, they are often ineffective due to low compliance. However, there have been few studies examining compliance on a product-by-product basis or in detail in Japan.
Kenji Kabeya, Hiroki Satoh, Natsuyo Yanagi, Yasufumi Sawada   +3 more
doaj   +1 more source

Innovation of Biomass Crusher by Application of Hardfacing Layers

Metals, 2021
This paper presents the innovation possibilities of the crushers functional parts and the results of layers’ renovation analyses of the surfaces worn by biomass crusher hammers.
Ján Viňáš, Janette Brezinová, Jakub Brezina, Peter Hermel   +3 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Persistence with topical glaucoma therapy in Japan from the perspective of product, formulation, and patient characteristics: analysis of medical insurance claim data

BMC Ophthalmology
Background Glaucoma is the leading cause of irreversible blindness in Japan and constitutes a serious public health challenge. Due to its asymptomatic onset and slow progression, patient persistence with topical glaucoma therapies remains low ...
Kenji Kabeya, Hiroki Satoh, Natsuyo Yanagi, Yasufumi Sawada   +3 more
doaj   +1 more source

Neutron lifetime measurements using gravitationally trapped ultracold neutrons

, 2009
Our experiment using gravitationally trapped ultracold neutrons (UCN) to measure the neutron lifetime is reviewed. Ultracold neutrons were trapped in a material bottle covered with perfluoropolyether.
A. G. Kharitonov, A. K. Fomin, A. P. Serebrov, A. V. Vassiljev, I. A. Krasnoschekova, M. S. Lasakov, O. M. Zherebtsov, P. Geltenbort, R. R. Taldaev, V. E. Varlamov, V. K. Ignatovich, V. V. Nesvizhevsky, V. V. Nesvizhevsky, W. Mampe, W. Mampe, Yu. N. Pokotilovski, Yu. N. Pokotilovski   +16 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Lifetime-aware cloud data centers: models and performance evaluation [PDF]

, 2016
We present a model to evaluate the server lifetime in cloud data centers (DCs). In particular, when the server power level is decreased, the failure rate tends to be reduced as a consequence of the limited number of components powered on.
Chiaraviglio, Luca, Cianfrani, Antonio, Listanti, Marco, Liu, William, Polverini, Marco   +4 more
core   +5 more sources

Instillation success rates among glaucoma eyedrop products: patient survey in Japan

BMC Ophthalmology
Background Glaucoma is the leading cause of blindness in Japan and poses a significant public health challenge. Previous studies have reported low success rates for antiglaucoma eyedrop instillation.
Kenji Kabeya, Hiroki Satoh, Natsuyo Yanagi, Yasufumi Sawada   +3 more
doaj   +1 more source

Lifetime Estrogen Exposure, Cumulative Lifetime Stress, and Cognition in Later Life [PDF]

, 2018
The main goal of this study was to begin to examine how stress and estrogen work together to influence memory and thinking in older women. We looked at how stressful experiences affected memory in older women and how the hormone estrogen influenced the ...
Senft Miller, Anna Erika
core   +1 more source

Network Lifetime Maximization for Cellular-Based M2M Networks

, 2017
High energy efficiency is critical for enabling massive machine-type communications (MTC) over cellular networks. This work is devoted to energy consumption modeling, battery lifetime analysis, lifetime-aware scheduling and transmit power control for ...
Azari, Amin, Miao, Guowang
core   +1 more source