Results 41 to 50 of about 20,457 (265)

Lifting of Coefficients for Chow Motives of Quadrics

open access: yes, 2010
We prove that the natural functor from the category of Chow motives of smooth projective quadrics with integral coefficients to the category with coefficients modulo 2 induces a bijection on the isomorphism classes of objects.
openaire   +2 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Hydrodynamic Forces of a Semi-Submerged Cylinder in an Oscillatory Flow

open access: yesApplied Sciences, 2020
This work experimentally investigated the performance of hydrodynamic forces on a semi-submerged cylinder under an oscillatory flow. To generate the equivalent oscillatory flow, the semi-submerged cylinder is forced to oscillate in several combinations ...
Haojie Ren   +5 more
doaj   +1 more source

Numerical Investigation of Performance Enhancement of the S809 Airfoil and Phase VI Wind Turbine Blade Using Co-Flow Jet Technology

open access: yesEnergies, 2021
Making full use of wind energy can effectively alleviate the global energy shortage and environment contamination problems. Nevertheless, how to significantly improve the performance of the wind turbine airfoil and blade is a crucial issue.
Shunlei Zhang, Xudong Yang, Bifeng Song
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

NUMERICAL SIMULATION ON REAR SPOILER ANGLE OF MINI MPV CAR FOR CONDUCTING STABILITY AND SAFETY

open access: yesJurnal Ilmiah SINERGI, 2019
Spoiler attached on the rear part of a car can generate drag force and negative lift force, called downforce. This drag force can increase air resistance to the car, meanwhile, a negative lift force can improve the car’s stability and safety.
Alief Avicenna Luthfie   +3 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Wind Tunnel Experimental Study of Lift Enhancement and Drag Reduction on a Swept Wing Based on a Co-Flow Jet Technique

open access: yesApplied Sciences
Co-flow jet (CFJ) is an active flow control technique that significantly enhances aerodynamic performance metrics such as the maximum lift and maximum lift-to-drag ratio of airfoils or wings.
Bo Wang   +3 more
doaj   +1 more source

Application of Convolutional Neural Network to Predict Airfoil Lift Coefficient [PDF]

open access: yes2018 AIAA/ASCE/AHS/ASC Structures, Structural Dynamics, and Materials Conference, 2018
The adaptability of the convolutional neural network (CNN) technique for aerodynamic meta-modeling tasks is probed in this work. The primary objective is to develop suitable CNN architecture for variable flow conditions and object geometry, in addition to identifying a sufficient data preparation process.
Yao Zhang, WoongJe Sung, Dimitri Mavris
openaire   +2 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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